CD82 (CD83) Antikörper

Antigen: CD82 (CD83)

Synonyme: BL11, HB15, R2, 4F9, C33, IA4, ST6, GR15, KAI1, SAR2, TSPAN27

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Ratte (Rattus), Maus

Applikation: Western Blot (WB)

Produktnummer: ABIN361202

Produktbeschreibung

Weitere Bezeichnung: CD82

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human CD82, different to the related mouse sequence by two amino acids

Format: Affinity-purified

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: CD82 (Cluster of Differentiation 82), also named KAI1, is a human protein encoded by the CD82 gene.The gene is mapped to 11p11.2. 1 This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. 2 The expression of CD82 protein appears to be correlated with lymph node metastasis in esophageal squamous cell carcinoma (ESCC). 3 And the CD82 overexpression can suppress tumor invasiveness and metastatic potential by inducing MMP9 inactivation via upregulation of TIMP1. 4

Anwendungen

Applikationshinweise: Recommended Dilutions: WB 1ug/ml

Reinigung: Immunogen affinity purified.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .

Lagerung: Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml. At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time.

Forschungsgebiet: Krebs, Transkriptionsfaktoren, CD Antigene, Adaptive Immunität, Oberflächenrezeptoren der Immunzellen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-CD82 (CD83) antibody