Apolioprotein A1 (APOA1) Antikörper

Antigen: Apolioprotein A1 (APOA1)

Synonyme: Sep2, Alp-1, Ltw-1, Sep-1, Sep-2, Apoa-1, Brp-14, Lvtw-1, MGC102525, apoA-I, apoa, cb49, MGC103718, wu:fb33f01, zgc:103718, APOA1, MGC64335, MGC89745, LOC100009253, ApoA-I, LOC100136573, apoa1, MGC117399, apoa-i

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Ratte (Rattus), Maus

Applikation: Western Blot (WB)

Produktnummer: ABIN361201

Produktbeschreibung

Weitere Bezeichnung: Apolipoprotein A-1, APOA1

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human APOA1, different to the related mouse sequence by two amino acids

Format: Affinity-purified

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Apolipoprotein A-1, also known as APOA1, is a human protein with a specific role in lipid metabolism. It binds to lipopolysaccharide or endotoxin, and has a major role in the anti-endotoxin function of HDL. 1 The gene is mapped to 11q23. And it is a single polypeptide chain with 243 amino acid residues of known primary amino acid sequence. 2 The ApoA-I protein promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. ApoA-I was also isolated as a prostacyclin (PGI2) stabilizing factor, and thus may have an anticlotting effect. 3 Defects in the gene encoding it are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis.Additionally, ApoA-I overexpression promotes macrophage-specific reverse cholesterol transport. 4

Synonyme: Sep2, Alp-1, Ltw-1, Sep-1, Sep-2, Apoa-1, Brp-14, Lvtw-1, MGC102525, apoA-I, apoa, cb49, MGC103718, wu:fb33f01, zgc:103718, APOA1, MGC64335, MGC89745, LOC100009253, ApoA-I, LOC100136573, apoa1, MGC117399, apoa-i

Anwendungen

Applikationshinweise: Recommended Dilutions: WB 1ug/ml

Reinigung: Immunogen affinity purified.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .

Lagerung: Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml. At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-Apolioprotein A1 (APOA1) antibody