Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cytotoxic Lymphocyte Maturation Factor 2, P40) (IL12B) Antikörper

Antigen: Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cytotoxic Lymphocyte Maturation Factor 2, P40) (IL12B)

Synonyme: CLMF, NKSF, CLMF2, NKSF2, IL-12B, p40, Il-12b, Il12p40, Il-12p40, Il12, IL12B, IL12A, IL-12p40, IL-12, il12b, IL-12 p40, MGC152789, il12p40.b, zgc:152789, IL-12.p40, Il12b, LOC100217488

Klonalität: Monoklonal (AT1D6)

Wirt: Maus

Reaktivität: Human, Ratte (Rattus)

Applikation: ELISA, Western Blot (WB)

Produktnummer: ABIN361135

Produktbeschreibung

Weitere Bezeichnung: IL12B

Immunogen: Recombinant human IL12B (23-328aa) purified from E. coli, Accession / GI number: NP_002178

Isotyp: IgG1, kappa chain  (Passende Sekundärantikörper)

Klon: AT1D6

Beschreibung: IL-12 is a heterodimer composed of subunits IL-12A p35 and IL-12B p40. Autocrine IL-12 is responsible for the differentiation of naive CD4+T cells into type 1 helper T cells (Th1) that produce interferon-gamma (IFN-gamma). Expression of STAT 4, a signal transduction molecule important in cytokine-induced gene expression, appears central to IL-12 induced Th1 production of IFN-gamma. It also activates production of tumor necrosis factor alpha (TNF alpha) from T and natural killer cells. IL-12 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. Synonyms: Interleukin 12B precursor

Anwendungen

Applikationshinweise: Recommended dilution 1:1000

Konzentration: 1mg/ml

Reinigung: The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

Buffer: In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide

Lagerung: Store at -20°, Aliquot to avoid repeated freezing and thawing.

Forschungsgebiet: Hormone, Zytokine

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cytotoxic Lymphocyte Maturation Factor 2, P40) (IL12B) antibody