NRG1(HRG-Beta3) Antikörper

Antigen: NRG1(HRG-Beta3)

Klonalität: Monoklonal (K1G13)

Wirt: Maus

Reaktivität: Human

Applikation: ELISA, Western Blot (WB)

Produktnummer: ABIN361097

Produktbeschreibung

Immunogen: Recombinant human NRG1 isoform HRG-beta3 (20-241aa), Accession / GI number: NP_039252

Isotyp: IgG1, kappa chain  (Passende Sekundärantikörper)

Klon: K1G13

Beschreibung: Neuregulin1 (NRG1) is one of four proteins in the neuregulin family that act on the Epidermal growth factor receptor (EGFR) family of receptors. NRG1 was originally identified as a 44 kDa glycoprotein that interacts with the ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. In many brain areas, NRG1 is expressed at synaptic regions and its processing can be regulated by neuronal activity. This variant (HRG-beta3) of NRG1, along with HRG-alpha, beta1 and beta2 variants, was identified in various normal tissues and cancer cell lines. Synonyms: neuregulin 1 isoform HRG-beta3

Anwendungen

Applikationshinweise: Recommended dilution 1:1000

Konzentration: 1mg/ml

Reinigung: The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

Buffer: In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide

Lagerung: Store at -20°, Aliquot to avoid repeated freezing and thawing.

Forschungsgebiet: Krebs

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-NRG1(HRG-Beta3) antibody