Flip Antikörper
| Antigen |
|
| Klonalität |
Monoklonal (5D8) |
|
Wirt
|
|
|
Reaktivität
|
|
|
Applikation
|
|
| Produktnummer |
ABIN361055 |
| Menge |
50ul (1mg/ml) (Varianten) |
| Preis |
230,77 € Zzgl. Versandkosten €20,00 und MWSt
|
| Lieferung nach |
|
| Verfügbarkeit |
Lieferung in 5 bis 7 Werktagen |
|
Immunogen
|
Recombinant human FLIP (1-376aa) , Accession / GI number: NP_003870
|
|
Isotyp
|
IgG3, kappa chain (Passende Sekundärantikörper)
|
|
Klon
|
5D8
|
|
Beschreibung
|
FLIP, also known as CASP8 and FADD-like apoptosis regulator (CFLAR), contains two death effector domains (DEDs) and a caspase-like domain. FLIP may play a crucial role between cell survival and cell death pathway in mammalian cells and interacts with adapter protein FADD and caspase-8 and -10, and potently inhibits apoptosis induced by all known death receptors DR3 (death receptor 3), TRAIL-R (TNF-related apoptosis-inducing ligand receptor) and TNFR1 (tumor necrosis factor receptor 1). Synonyms: CASP8 and FADD-like apoptosis regulator isoform 1
|
|
Applikationshinweise
|
Recommended dilution 1:500
|
|
Konzentration
|
1mg/ml
|
|
Reinigung
|
The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
|
|
Buffer
|
In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
|
|
Lagerung
|
Store at -20°, Aliquot to avoid repeated freezing and thawing.
|
|
Forschungsgebiet
|
Signaltransduktion
|
|
Beschränkungen
|
Nur für Forschungszwecke einsetzbar
|
Alternativen zu Antigen "Flip", Typ "Antikörper" finden
|
Wirte
|
Kaninchen (41), Maus (2)
|
|
Reaktivitäten
|
Human (43), Maus (37), Ratte (Rattus) (37), Rind (Kuh) (35), Hund (34), Kaninchen (34), Schwein (31), Pferd (19), Huhn (15)
|
|
Applikationen
|
Durchflusszytometrie (FACS) (36), Immunfluoreszenz (IF) (36), Western Blot (WB) (9), ELISA (8), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (4), Immunhistochemie (Paraffinschnitte) (IHC (p)) (4), Immunpräzipitation (IP) (4), Immunoelectron Microscopy (IEM) (2)
|
|
Konjugate
|
Alexa Flour 488 (2), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Biotin (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), FITC (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2), RBITC (2)
|