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zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (Center) Antikörper

Antigen

zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70)

Synonyme SRK, STD, TZK, ZAP-70, FLJ17670, FLJ17679, Srk, mur, 70kDa, mrtle, AI327364, MGC108902, zap70, MGC80670, MGC88962, ZAP70
Epitope
Alternativen

Center

Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Human

Applikation
Alternativen Enzyme Immunoassay (EIA), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)
Produktnummer ABIN360165
Menge 0.1 mg  (0.25 mg/ml)
Preis 330,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Produktmerkmale Synonyms: ZAP-70, ZAP 70, SRK, 70 kDa zeta-associated protein, Syk-related tyrosine kinase
Weitere Bezeichnung ZAP70
Gen-ID 7535
Swiss-Prot P43403
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated syntheticpeptide selected from the center region of human ZAP70.
Kreuzreaktivität Human
Isotyp Ig  (Passende Sekundärantikörper)
Beschreibung This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it playsa role in T-cell development and lymphocyte activation. This enzyme, which isphosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation,functions in the initial step of TCR-mediated signal transduction in combination with theSrc family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiencydisease characterized by a selective absence of CD8-positive T-cells. Two transcriptvariants that encode different isoforms have been found for this gene.
Spezifität This antibody reacts to ZAP70. Species: Human. Others not tested.

Anwendungen

Applikationshinweise ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Konzentration 0.25 mg/ml
Reinigung Purified
Buffer PBS with 0.09% (W/V) sodium azide
Lagerung Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70)", Typ "Antikörper" finden
Wirte Kaninchen (117), Maus (74)
Reaktivitäten Human (187), Maus (91), Ratte (Rattus) (66), Rind (Kuh) (18), Schwein (18), Hund (17), Pferd (16), Kaninchen (16), Huhn (15), Meerschweinchen (15)
Applikationen Western Blot (WB) (101), Durchflusszytometrie (FACS) (58), Immunfluoreszenz (IF) (35), Immunhistochemie (Paraffinschnitte) (IHC (p)) (34), Immunhistochemie (IHC) (33), ELISA (32), Immunpräzipitation (IP) (23), Enzyme Immunoassay (EIA) (20), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (9), Intrazelluläre Durchflusszytometrie (ICFC) (6), Immunzytochemie (ICC) (4), Dot Blot (Dot) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), ELISA (Detektionsantikörper) (1), Immunoelectron Microscopy (IEM) (1)
Konjugate FITC (11), PE (10), Biotin (9), Alkaline Phosphatase (AP) (4), HRP (3), PerCP,Cy5.5 (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1), RPE (1)
Epitope pTyr319 (10), pTyr493 (8), Ab-319 (5), Ab-493 (5), C-Term (5), pTyr292 (4), Center (2), AA 319-602 (1), Ab-292 (1), Ab-315 (1), pTyr315 (1), pTyr492 (1), pYTyr315/319 (1)