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Antikörper
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anti-Tyrosine-Protein Kinase ZAP-70 ZAP70 Center
Tyrosine-Protein Kinase ZAP-70 (ZAP70) (Center) Antikörper
| Antigen |
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| Synonyme |
SRK, STD, TZK, ZAP-70, FLJ17670, FLJ17679 |
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Epitope
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| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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Alternativen Enzyme Immunoassay (EIA), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)
Western Blot (WB) (80), Durchflusszytometrie (FACS) (45), ELISA (38), Immunhistochemie (IHC) (27), Immunhistochemie (Paraffinschnitte) (IHC (p)) (27), Immunfluoreszenz (IF) (26), Immunpräzipitation (IP) (20), Enzyme Immunoassay (EIA) (13), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (11), Intrazelluläre Durchflusszytometrie (ICFC) (6), Immunzytochemie (ICC) (3), Dot Blot (Dot) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), ELISA (Detektionsantikörper) (1), Immunelektronenmikroskopie (EM) (1)
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| Produktnummer |
ABIN360165 |
| Menge |
0.1 mg (0.25 mg/ml) |
| Preis |
315,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Versandbereit innerhalb von 7 bis 10 Werktagen |
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Produktmerkmale
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Synonyms: ZAP-70, ZAP 70, SRK, 70 kDa zeta-associated protein, Syk-related tyrosine kinase
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Weitere Bezeichnung
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ZAP70 (Center)
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Gen-ID
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7535
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Swiss-Prot
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P43403
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Immunogen
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This antibody is generated from rabbits immunized with a KLH conjugated syntheticpeptide selected from the center region of human ZAP70.
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Isotyp
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Ig (Passende Sekundärantikörper)
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Beschreibung
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This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it playsa role in T-cell development and lymphocyte activation. This enzyme, which isphosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation,functions in the initial step of TCR-mediated signal transduction in combination with theSrc family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiencydisease characterized by a selective absence of CD8-positive T-cells. Two transcriptvariants that encode different isoforms have been found for this gene.
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Spezifität
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This antibody reacts to ZAP70. Species: Human. Others not tested.
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Applikationshinweise
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Konzentration
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0.25 mg/ml
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Buffer
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PBS with 0.09% (W/V) sodium azide
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Lagerung
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Tyrosine-Protein Kinase ZAP-70 (ZAP70)", Typ "Antikörper" finden
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Wirte
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Kaninchen (89), Maus (75)
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Reaktivitäten
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Human (161), Maus (81), Ratte (Rattus) (54), Huhn (15), Rind (Kuh) (15), Hund (15), Meerschweinchen (15), Pferd (15), Schwein (15), Kaninchen (15)
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Applikationen
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Western Blot (WB) (80), Durchflusszytometrie (FACS) (45), ELISA (38), Immunhistochemie (IHC) (27), Immunhistochemie (Paraffinschnitte) (IHC (p)) (27), Immunfluoreszenz (IF) (26), Immunpräzipitation (IP) (20), Enzyme Immunoassay (EIA) (13), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (11), Intrazelluläre Durchflusszytometrie (ICFC) (6), Immunzytochemie (ICC) (3), Dot Blot (Dot) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), ELISA (Detektionsantikörper) (1), Immunelektronenmikroskopie (EM) (1)
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Konjugate
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FITC (9), PE (9), Biotin (8), AP (5), HRP (4), PerCP/Cy5.5 (2), Alexa Flour 488 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1)
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Epitope
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pTyr319 (10), Ab-319 (5), Ab-493 (5), pTyr493 (5), Center (2), pTyr292 (2), Ab-292 (1), Ab-315 (1), pTyr315 (1), pYTyr315/319 (1)
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