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ANTXR1 Antikörper (Tyr382)

ANTXR1 Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN360040
  • Target Alle ANTXR1 Antikörper anzeigen
    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
    Bindungsspezifität
    • 15
    • 9
    • 8
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 365-394, Tyr382
    Reaktivität
    • 75
    • 40
    • 22
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 69
    • 3
    • 3
    Kaninchen
    Klonalität
    • 72
    • 3
    Polyklonal
    Konjugat
    • 34
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ANTXR1 Antikörper ist unkonjugiert
    Applikation
    • 47
    • 30
    • 15
    • 13
    • 13
    • 11
    • 8
    • 4
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody recognizesANTXR1.
    Aufreinigung
    Affinity Chromatography on Protein A
    Immunogen
    KLH conjugated synthetic peptide between 365~394 amino acids surrounding Tyr382 of Human ANTXR1.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product ANTXR1 Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Western blotting: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
    Andere Bezeichnung
    Anthrax Toxin Receptor 1 (ANTXR1 Produkte)
    Synonyme
    ANTXR1 antikoerper, ATR antikoerper, TEM8 antikoerper, 2310008J16Rik antikoerper, 2810405N18Rik antikoerper, Antrx1 antikoerper, Tem8 antikoerper, anthrax toxin receptor 1 antikoerper, ANTXR1 antikoerper, Antxr1 antikoerper
    Hintergrund
    ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.Synonyms: ANTXR1, ATR, TEM8, Tumor endothelial marker 8
    Gen-ID
    84168, 9606
    UniProt
    Q9H6X2
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