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TIE1 Antikörper (N-Term)

TIE1 Reaktivität: Human, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN359947
  • Target Alle TIE1 Antikörper anzeigen
    TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
    Bindungsspezifität
    • 15
    • 10
    • 9
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 93
    • 36
    • 33
    • 1
    Human, Maus
    Wirt
    • 76
    • 18
    • 1
    Kaninchen
    Klonalität
    • 77
    • 18
    Polyklonal
    Konjugat
    • 35
    • 9
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TIE1 Antikörper ist unkonjugiert
    Applikation
    • 74
    • 45
    • 23
    • 13
    • 13
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects TIE1 at N-term.
    Aufreinigung
    Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human TIE.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product TIE1 Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/10-1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
    Andere Bezeichnung
    TIE1 (TIE1 Produkte)
    Synonyme
    JTK14 antikoerper, TIE antikoerper, D430008P04Rik antikoerper, tie-1 antikoerper, tyrosine kinase with immunoglobulin like and EGF like domains 1 antikoerper, tyrosine kinase with immunoglobulin-like and EGF-like domains 1 antikoerper, tyrosine-protein kinase receptor Tie-1 antikoerper, endothelium-specific receptor tyrosine kinase 1 antikoerper, TIE1 antikoerper, Tie1 antikoerper, CpipJ_CPIJ018933 antikoerper, tie1 antikoerper
    Hintergrund
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: TIE, Tie-1, Tyrosine-protein kinase receptor Tie-1
    Molekulargewicht
    125089 Da
    Gen-ID
    7075, 9606
    UniProt
    P35590
    Pathways
    RTK Signalweg
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