EPH Receptor B3 Antikörper (N-Term)

Produktnummer ABIN359815

Produktdetails anti-EPH Receptor B3 Antikörper

Target: EPH Receptor B3 (EPHB3)

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor B3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to EphB3.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human EphB3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu EPH Receptor B3

Target: EPH Receptor B3 (EPHB3)

Andere Bezeichnung: EPHB3 (EPHB3 Produkte)

Synonyme: tck antikoerper, MGC83457 antikoerper, EPHB3 antikoerper, ETK2 antikoerper, HEK2 antikoerper, TYRO6 antikoerper, AW456895 antikoerper, Cek10 antikoerper, Etk2 antikoerper, MDK5 antikoerper, Sek4 antikoerper, Tyro6 antikoerper, CEK10 antikoerper, EK10 antikoerper, ek3 antikoerper, ephb3 antikoerper, fc62d03 antikoerper, rtk3 antikoerper, wu:fc62d03 antikoerper, zek3 antikoerper, EPH receptor B3 antikoerper, EPH receptor B3 L homeolog antikoerper, Eph receptor B3 antikoerper, eph receptor B3a antikoerper, Eph receptor tyrosine kinase antikoerper, EPHB3 antikoerper, ephb3.L antikoerper, ephb3 antikoerper, Ephb3 antikoerper, ephb3a antikoerper

Hintergrund: Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB3, a member of the Tyr family of protein kinases, is a receptor for members of the ephrin-B family, it binds to both ephrin-B1 and -B2. Expression of this Type I membrane protein is ubiquitous. The protein contains putative domains for 2 fibronectin type III and 1 sterile alpha motif (SAM).Synonyms: ETK2, Ephrin type-B receptor 3, HEK2, TYRO6, Tyrosine-protein kinase TYRO6, Tyrosine-protein kinase receptor HEK-2

Gen-ID: 2049, 9606

UniProt: P54753

Pathways: RTK Signalweg