ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (C-Term) Antikörper

Antigen: ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4)

Synonyme: ADMP-1, ADAMTS-2, ADAMTS-4, KIAA0688, KIAA0366, ADAM-TS4, mKIAA0688, 3830423K05, ADAMTS4, DKFZp469J0817, AAC2, PNAT, NPI, PCINP, PCPNI, hPCPNI, ADAM-TS2, ADAMTS-3, TTP, VWFCP, C9orf8, vWF-CP, FLJ42993, MGC118899, MGC118900, DKFZp434C2322, ADMP-2, ADAMTS11, FLJ36738, ASMP-2, ADAMTS1, ADAM-TS5, AI481094, 9530092O11Rik, PWTSR, THSD2, CRISTIN1, FLJ14440, AW743315, 1810011L16Rik, 8430403M15Rik, E030027K14Rik, FLJ16042, AU015154, 4831407I23Rik, D230034E10Rik, Gm710, ADAMTS5, ADAMTS13, ADAMTS-11

Epitope: C-Term

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Enzyme Immunoassay (EIA), Western Blot (WB)

Produktnummer: ABIN359602

Produktbeschreibung

Produktmerkmale: Synonyms: ADAMTS-4, ADAM-TS4, Aggrecanase-1, ADMP1, ADMP-1, KIAA0688, A disintegrin andmetalloproteinase with thrombospondin motifs 4

Weitere Bezeichnung: ADAMTS4

Gen-ID: 9507

Swiss-Prot: O75173

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated syntheticpeptide selected from the C-terminal region of human ADAMTS4.

Kreuzreaktivität: Human, Maus

Isotyp: Ig  (Passende Sekundärantikörper)

Beschreibung: ADAMTS4 is a member of the ADAMTS (a disintegrin and metalloproteinase withthrombospondin motifs) protein family. Members of the family share several distinctprotein modules, including a propeptide region, a metalloproteinase domain, adisintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members ofthis family differ in the number of C-terminal TS motifs, and some have unique C-terminaldomains. The enzyme lacks a C-terminal TS motif. It is responsible for the degradation ofaggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellularmatrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme inarthritic disease and in the central nervous system, potentially, in the progression ofglioma.

Spezifität: This antibody reacts to ADAMTS4. Species: Human, Mouse. Others not tested.

Synonyme: ADMP-1, ADAMTS-2, ADAMTS-4, KIAA0688, KIAA0366, ADAM-TS4, mKIAA0688, 3830423K05, ADAMTS4, DKFZp469J0817, AAC2, PNAT, NPI, PCINP, PCPNI, hPCPNI, ADAM-TS2, ADAMTS-3, TTP, VWFCP, C9orf8, vWF-CP, FLJ42993, MGC118899, MGC118900, DKFZp434C2322, ADMP-2, ADAMTS11, FLJ36738, ASMP-2, ADAMTS1, ADAM-TS5, AI481094, 9530092O11Rik, PWTSR, THSD2, CRISTIN1, FLJ14440, AW743315, 1810011L16Rik, 8430403M15Rik, E030027K14Rik, FLJ16042, AU015154, 4831407I23Rik, D230034E10Rik, Gm710, ADAMTS5, ADAMTS13, ADAMTS-11

Anwendungen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Konzentration: 0.25 mg/ml

Reinigung: Aff - Purified

Buffer: PBS with 0.09% (W/V) sodium azide

Lagerung: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Beschränkungen: Nur für Forschungszwecke einsetzbar