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MAP3K12 Antikörper (C-Term)

MAP3K12 Reaktivität: Human, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN359408
  • Target Alle MAP3K12 Antikörper anzeigen
    MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))
    Bindungsspezifität
    • 9
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 36
    • 20
    • 12
    Human, Maus
    Wirt
    • 35
    • 2
    Kaninchen
    Klonalität
    • 35
    • 2
    Polyklonal
    Konjugat
    • 13
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MAP3K12 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 24
    • 17
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects MAP3K12 at C-term.
    Aufreinigung
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ZPK.
    Isotyp
    Ig Fraction
  • Applikationshinweise
    ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Target
    MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))
    Andere Bezeichnung
    MAP3K12 (MAP3K12 Produkte)
    Synonyme
    DLK antikoerper, MEKK12 antikoerper, MUK antikoerper, ZPK antikoerper, ZPKP1 antikoerper, PK antikoerper, Zpk antikoerper, zgc:77370 antikoerper, MGC151798 antikoerper, dlk antikoerper, map3k12 antikoerper, map3k12a antikoerper, mekk12 antikoerper, muk antikoerper, zpk antikoerper, zpkp1 antikoerper, DKFZp459K2433 antikoerper, map3k12-a antikoerper, map3k12-b antikoerper, map3k12b antikoerper, mitogen-activated protein kinase kinase kinase 12 antikoerper, mitogen activated protein kinase kinase kinase 12 antikoerper, mitogen-activated protein kinase kinase kinase 12 S homeolog antikoerper, mitogen-activated protein kinase kinase kinase 12 L homeolog antikoerper, MAP3K12 antikoerper, Map3k12 antikoerper, map3k12 antikoerper, map3k12.S antikoerper, map3k12.L antikoerper
    Hintergrund
    ZPK is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation.Synonyms: Dual leucine zipper bearing kinase, Leucine-zipper protein kinase, MAPK-upstream kinase, Mitogen-activated protein kinase kinase kinase 12, Mixed lineage kinase
    Molekulargewicht
    93188 Da
    Gen-ID
    7786, 9606
    UniProt
    Q12852
    Pathways
    MAPK Signalweg
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