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MKNK1 Antikörper (N-Term)

MKNK1 Reaktivität: Human WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN359308
  • Target Alle MKNK1 Antikörper anzeigen
    MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))
    Bindungsspezifität
    • 10
    • 8
    • 8
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 68
    • 36
    • 30
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 62
    • 9
    Kaninchen
    Klonalität
    • 63
    • 8
    Polyklonal
    Konjugat
    • 52
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MKNK1 Antikörper ist unkonjugiert
    Applikation
    • 55
    • 51
    • 12
    • 12
    • 9
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to MKNK1.
    Aufreinigung
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MKNK1.
    Isotyp
    Ig Fraction
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    Discover our top product MKNK1 Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))
    Andere Bezeichnung
    MKNK1 (MKNK1 Produkte)
    Synonyme
    MNK1 antikoerper, MKNK1 antikoerper, zgc:171912 antikoerper, 2410048M24Rik antikoerper, Mnk1 antikoerper, MAPK signal-integrating kinase 1 antikoerper, mknk1 antikoerper, mnk1 antikoerper, MAP kinase interacting serine/threonine kinase 1 antikoerper, MAP kinase-interacting serine/threonine kinase 1 antikoerper, MAP kinase interacting serine/threonine kinase 1 S homeolog antikoerper, MKNK1 antikoerper, mknk1 antikoerper, Mknk1 antikoerper, mknk1.S antikoerper
    Hintergrund
    MKNK1 encodes a predicted 424-amino acid protein containing a sequence typical of the catalytic domain of serine/threonine kinases and a putative N-terminal nuclear localization signal sequence.C-terminal region of MKNK1 was phosphorylated and activated in vivo and in vitro by ERK1 and p38 MAP kinases, but not by JNK/SAPK. The activated ERK is essential for the activation of MKNK1 in insect cells. MKNK1 was activated following stimulation of HeLa cells with a variety of extracellular stimuli. MNK1 bind tightly to the growth factor-regulated MAP kinases, Erk1 and Erk2, and also binds strongly to the stress-activated kinase, p38.Synonyms: MAP kinase-interacting serine/threonine-protein kinase 1, MNK1
    Gen-ID
    8569, 9606
    UniProt
    Q9BUB5
    Pathways
    MAPK Signalweg, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor
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