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Ketohexokinase Antikörper (N-Term)

KHK Reaktivität: Human, Maus WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN359149
  • Target Alle Ketohexokinase (KHK) Antikörper anzeigen
    Ketohexokinase (KHK)
    Bindungsspezifität
    • 15
    • 13
    • 10
    • 9
    • 8
    • 8
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 77
    • 34
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 72
    • 4
    • 1
    Kaninchen
    Klonalität
    • 74
    • 3
    Polyklonal
    Konjugat
    • 31
    • 7
    • 6
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Ketohexokinase Antikörper ist unkonjugiert
    Applikation
    • 64
    • 39
    • 13
    • 13
    • 12
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to Ketohexokinase (KHK).
    Aufreinigung
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human KHK.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product KHK Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    Ketohexokinase (KHK)
    Andere Bezeichnung
    Ketohexokinase (KHK Produkte)
    Hintergrund
    Ketohexokinase (KHK), or fructokinase, catalyzes conversion of fructose to fructose-1-phosphate. Splice variant 1 is the highly active form found in liver, renal cortex, and small intestine, while splice variant 2 is the lower activity form found in most other tissues. KHK, like glucokinase (GCK) and glucokinase regulator (GCKR), is present in both liver and pancreatic islets. The inhibition of GCK by GCKR is blocked by binding of fructose-1-phosphate to GCKR. The chromosomal proximity of the metabolically connected GCKR and KHK genes has a genetic linkage in type 2 diabetes. Fructosuria, or hepatic fructokinase deficiency, is a benign, asymptomatic defect of intermediary metabolism associated with heterozygosity for G50R and A43T mutations in KHK.Synonyms: EC=2.7.1.3, Hepatic fructokinase, KHK, Ketohexokinase
    Gen-ID
    3795, 9606
    UniProt
    P50053
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