Claudin 1 Antikörper (Loop 1)

Produktnummer ABIN358846

Produktdetails anti-Claudin 1 Antikörper

Target: Claudin 1 (CLDN1)

Bindungsspezifität: Loop 1

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to Claudin 1 (CLDN1).

Aufreinigung: Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Loop1 region of human CLDN1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu Claudin 1

Target: Claudin 1 (CLDN1)

Andere Bezeichnung: Claudin-1 / CLDN1 (CLDN1 Produkte)

Synonyme: CLD1 antikoerper, ILVASC antikoerper, SEMP1 antikoerper, AI596271 antikoerper, cldn19 antikoerper, claudin-1 antikoerper, cld1 antikoerper, ilvasc antikoerper, semp1 antikoerper, CLDN1 antikoerper, claudin 1 antikoerper, claudin 1 S homeolog antikoerper, CLDN1 antikoerper, Cldn1 antikoerper, cldn1 antikoerper, cldn1.S antikoerper

Hintergrund: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. CLDN1, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.Synonyms: CLD1, PRO944, SEMP1, Senescence-associated epithelial membrane protein, UNQ481

Gen-ID: 9076, 9606

UniProt: O95832

Pathways: Cell-Cell Junction Organization, Hepatitis C