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EIF4E Antikörper (pSer209)
EIF4E
Reaktivität: Human
EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-EIF4E Antikörper
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Target
Alle EIF4E Antikörper anzeigen
EIF4E
(Eukaryotic Translation Initiation Factor 4E (EIF4E))
Bindungsspezifität
Alle Epitope für EIF4E Antikörper
pSer209
Reaktivität
Alle Reaktivitäten für EIF4E Antikörper
Human
Wirt
Alle Wirte für EIF4E Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für EIF4E Antikörper
Polyklonal
Konjugat
Alle Konjugate für EIF4E Antikörper
Dieser EIF4E Antikörper ist unkonjugiert
Applikation
Alle Applikationen für EIF4E Antikörper
Enzyme Immunoassay (EIA)
Spezifität
This antibody detectsEIF4E pSer209.
Aufreinigung
Affinity purification in a 2-step procedure with the control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen
This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S209 of human EIF4E.
Isotyp
Ig Fraction
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
ELISA: 1/1,000. Dot Blot: 1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium Azide as preservative.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Details zu EIF4E
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Target
EIF4E
(Eukaryotic Translation Initiation Factor 4E (EIF4E))
Andere Bezeichnung
EIF4E (EIF4E Produkte )
Synonyme
AUTS19 antikoerper, CBP antikoerper, EIF4E1 antikoerper, EIF4EL1 antikoerper, EIF4F antikoerper, eif4e-1 antikoerper, zgc:86680 antikoerper, EG668879 antikoerper, Eif4e-ps antikoerper, If4e antikoerper, eIF-4E antikoerper, 0260/09 antikoerper, 0587/11 antikoerper, 0589/11 antikoerper, 0919/12 antikoerper, 1004/13 antikoerper, 2 antikoerper, 7238 antikoerper, CG4035 antikoerper, CT13384 antikoerper, CT39424 antikoerper, CT39426 antikoerper, D-eIF4E antikoerper, Dmel\\CG4035 antikoerper, Eif4E antikoerper, Eif4e antikoerper, IF4E antikoerper, dEif4e antikoerper, deIF-4E antikoerper, deIF4E antikoerper, eIF 4E antikoerper, eIF-4E1 antikoerper, eIF-4E2 antikoerper, eIF-4EII antikoerper, eIF-4e antikoerper, eIF4E antikoerper, eIF4E-1 antikoerper, eIF4E-1/2 antikoerper, eIF4E-2 antikoerper, eIF4E1 antikoerper, eIF4EI antikoerper, eIF4e antikoerper, eif-4E antikoerper, eif-4e antikoerper, eif4e antikoerper, l(3)07238 antikoerper, l(3)67Af antikoerper, l(3)S025007 antikoerper, l(3)S026009 antikoerper, l(3)S058711 antikoerper, l(3)S091912 antikoerper, cbp antikoerper, eif4f antikoerper, eif4e1 antikoerper, eif4el1 antikoerper, EIF-4E antikoerper, zgc:101581 antikoerper, eukaryotic translation initiation factor 4E antikoerper, eukaryotic translation initiation factor 4ea antikoerper, Eukaryotic initiation factor 4E antikoerper, eucaryotic initiation factor 6 antikoerper, eukaryotic translation initiation factor 4E L homeolog antikoerper, eukaryotic translation initiation factor 4E family member 1B S homeolog antikoerper, translation initiation factor eIF4E antikoerper, eukaryotic translation initiation factor 4eb antikoerper, EIF4E antikoerper, eif4ea antikoerper, Eif4e antikoerper, eIF-4E antikoerper, eif6 antikoerper, eif4e antikoerper, eif4e.L antikoerper, eif4e1b.S antikoerper, LOC100533326 antikoerper, eif4eb antikoerper
Hintergrund
EIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. EIF4E is also known to interact with other partners. The interaction with EIF4ENIF1 mediates the import into the nucleus. Nonphosphorylated EIF4EBP1, EIF4EBP2 and EIF4EBP3 compete with EIF4G1/EIF4G3 to interact with EIF4E, insulin stimulated MAP-kinase (MAPK1 and MAPK3) phosphorylation of EIF4EBP1 causes dissociation of the complex allowing EIF4G1/EIF4G3 to bind and consequent initiation of translation. Rapamycin can attenuate insulin stimulation, mediated by FKBPs.Synonyms: EIF-4E, EIF4EL1, EIF4F, Eukaryotic translation initiation factor 4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein
Molekulargewicht
25097 Da
Gen-ID
1977, 9606
UniProt
P06730
Pathways
BCR Signaling
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