RPS6KA3 Antikörper (pSer369)

Produktnummer ABIN358394

Produktdetails anti-RPS6KA3 Antikörper

Target: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Bindungsspezifität: pSer369

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPS6KA3 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Spezifität: This antibody detects RPS6KA3 pSer369. Predicted to cross react with Mouse and Zebrafish (100 % Antigen Homology).

Aufreinigung: Affinity purification in a 2-step procedure with the control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S369 of human RPS6KA3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu RPS6KA3

Target: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Andere Bezeichnung: RPS6KA3 / RSK2 (RPS6KA3 Produkte)

Synonyme: HU-1 antikoerper, MAPKAPK1A antikoerper, RSK antikoerper, RSK1 antikoerper, CLS antikoerper, HU-3 antikoerper, ISPK-1 antikoerper, MAPKAPK1B antikoerper, MRX19 antikoerper, RSK2 antikoerper, S6K-alpha3 antikoerper, p90-RSK2 antikoerper, pp90RSK2 antikoerper, MPK-9 antikoerper, Rsk2 antikoerper, RGD1563860 antikoerper, id:ibd1103 antikoerper, rps6ka3 antikoerper, si:ch211-114c12.12 antikoerper, wu:fk86e02 antikoerper, zgc:56006 antikoerper, zgc:158386 antikoerper, ribosomal protein S6 kinase A1 antikoerper, ribosomal protein S6 kinase A3 antikoerper, ribosomal protein S6 kinase polypeptide 3 antikoerper, ribosomal protein S6 kinase a, polypeptide 3a antikoerper, ribosomal protein S6 kinase, polypeptide 3b antikoerper, RPS6KA1 antikoerper, RPS6KA3 antikoerper, Rps6ka3 antikoerper, rps6ka3a antikoerper, rps6ka3b antikoerper

Hintergrund: RSK3 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in the gene have been associated with Coffin-Lowry syndrome (CLS).Synonyms: ISPK-1, ISPK1, MAPKAPK-1b, MAPKAPK1, RSK-2, Ribosomal S6 kinase 2, Ribosomal protein S6 kinase alpha-3, S6K-alpha-3, p90RSK3

Molekulargewicht: 83736 Da

Gen-ID: 6197, 9606

UniProt: P51812

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades