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c-MYC Antikörper (pThr58)

MYC Reaktivität: Human WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN358293
  • Target Alle c-MYC (MYC) Antikörper anzeigen
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    Bindungsspezifität
    • 55
    • 44
    • 44
    • 40
    • 24
    • 21
    • 19
    • 16
    • 15
    • 11
    • 11
    • 11
    • 10
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr58
    Reaktivität
    • 375
    • 170
    • 123
    • 15
    • 14
    • 13
    • 13
    • 13
    • 9
    • 9
    • 8
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 296
    • 99
    • 7
    • 3
    • 2
    • 1
    Kaninchen
    Klonalität
    • 287
    • 120
    Polyklonal
    Konjugat
    • 197
    • 32
    • 27
    • 26
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser c-MYC Antikörper ist unkonjugiert
    Applikation
    • 307
    • 142
    • 96
    • 83
    • 80
    • 66
    • 58
    • 28
    • 26
    • 17
    • 15
    • 14
    • 12
    • 11
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects MYC pThr58. Predicted to cross react with Mouse and Zebrafish (100 % Antigen Homology).
    Aufreinigung
    Protein A Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T58 of human MYC.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product MYC Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Dot Blot: 1/100-1/500. Western Blot: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    Andere Bezeichnung
    C-Myc (MYC Produkte)
    Synonyme
    MRTL antikoerper, MYCC antikoerper, bHLHe39 antikoerper, c-Myc antikoerper, CMYC antikoerper, c-myc antikoerper, C-MYC antikoerper, LOC100136746 antikoerper, ARC antikoerper, B430311C09Rik antikoerper, MYC antikoerper, NOP antikoerper, Nop30 antikoerper, RNCMYC antikoerper, mMyc antikoerper, AU016757 antikoerper, Myc2 antikoerper, Niard antikoerper, Nird antikoerper, cmyc antikoerper, zc-myc antikoerper, c-myc II antikoerper, myc-B antikoerper, myc2 antikoerper, myc1 antikoerper, CMyc antikoerper, zgc:55680 antikoerper, CG10798 antikoerper, D-Myc antikoerper, DM antikoerper, DMYc antikoerper, Dm antikoerper, Dmel\CG10798 antikoerper, Dmyc antikoerper, EG:BACN5I9.1 antikoerper, anon-WO03040301.171 antikoerper, bHLHe57 antikoerper, c-MYC antikoerper, d-myc antikoerper, dMYC antikoerper, dMyc antikoerper, dMyc1 antikoerper, da antikoerper, dm antikoerper, dm/dMyc antikoerper, dm/myc antikoerper, dmyc antikoerper, dmyc1 antikoerper, l(1)G0139 antikoerper, l(1)G0354 antikoerper, l(1)G0359 antikoerper, myc antikoerper, MYC proto-oncogene, bHLH transcription factor antikoerper, v-myc myelocytomatosis viral oncogene homolog antikoerper, nucleolar protein 3 (apoptosis repressor with CARD domain) antikoerper, myelocytomatosis oncogene antikoerper, MYC proto-oncogene, bHLH transcription factor a antikoerper, MYC proto-oncogene, bHLH transcription factor L homeolog antikoerper, MYC proto-oncogene, bHLH transcription factor S homeolog antikoerper, v-myc myelocytomatosis viral oncogene homolog (avian) antikoerper, MYC proto-oncogene, bHLH transcription factor b antikoerper, CG10798 gene product from transcript CG10798-RB antikoerper, MYC antikoerper, LOC100136746 antikoerper, Nol3 antikoerper, Myc antikoerper, myca antikoerper, myc.L antikoerper, myc.S antikoerper, mycb antikoerper
    Hintergrund
    MYC participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.Synonyms: BHLHE39, Class E basic helix-loop-helix protein 39, Myc proto-oncogene protein, Transcription factor p64
    Molekulargewicht
    50434 Da
    Gen-ID
    4609, 9606
    UniProt
    P01106
    Pathways
    p53 Signalweg, Zellzyklus, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effekt
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