RFC5 Antikörper (Middle Region)

Produktnummer ABIN357979

Produktdetails anti-RFC5 Antikörper

Target: RFC5 (Replication Factor C (Activator 1) 5, 36.5kDa (RFC5))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RFC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects RFC5 (Center).

Aufreinigung: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human RFC5.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western Blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu RFC5

Target: RFC5 (Replication Factor C (Activator 1) 5, 36.5kDa (RFC5))

Andere Bezeichnung: RFC5 / RFC36 (RFC5 Produkte)

Synonyme: zgc:110313 antikoerper, 2610020K06Rik antikoerper, 2610209F07Rik antikoerper, 36.5kDa antikoerper, 36kDa antikoerper, Recc5 antikoerper, RFC36 antikoerper, replication factor C (activator 1) 5 antikoerper, replication factor C subunit 5 antikoerper, replication factor C subunit 5 L homeolog antikoerper, rfc5 antikoerper, Rfc5 antikoerper, RFC5 antikoerper, rfc5.L antikoerper

Hintergrund: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. RFC5 is the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system.Synonyms: Activator 1 36 kDa subunit, Activator 1 subunit 5, RF-C 36 kDa subunit, Replication factor C 36 kDa subunit, Replication factor C subunit 5

Molekulargewicht: 38497 Da

Gen-ID: 5985, 9606

UniProt: P40937

Pathways: Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA