GCS1 Antikörper (N-Term)

Produktnummer ABIN357669

Produktdetails anti-GCS1 Antikörper

Target: GCS1 (MOGS) (Mannosyl-Oligosaccharide Glucosidase (MOGS))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody is specific to GCS1 (N-term).

Aufreinigung: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human GCS1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western Blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu GCS1

Target: GCS1 (MOGS) (Mannosyl-Oligosaccharide Glucosidase (MOGS))

Andere Bezeichnung: MOGS / GCS1 (MOGS Produkte)

Synonyme: Afu6g04210 antikoerper, AO090701000141 antikoerper, Mogs antikoerper, CDG2B antikoerper, CWH41 antikoerper, DER7 antikoerper, GCS1 antikoerper, 1810017N02Rik antikoerper, AI181835 antikoerper, Gcs1 antikoerper, gcs1 antikoerper, im:7160827 antikoerper, wu:fe50a12 antikoerper, wu:fk09a10 antikoerper, zgc:158312 antikoerper, mannosyl-oligosaccharide glucosidase antikoerper, mannosyl-oligosaccharide glucosidase GCS1 antikoerper, mannosyl-oligosaccharide glucosidase L homeolog antikoerper, mannosyl oligosaccharide glucosidase antikoerper, glucosidase 1 antikoerper, AFUA_6G04210 antikoerper, Tc00.1047053511015.10 antikoerper, Tc00.1047053511805.10 antikoerper, LOC5576381 antikoerper, AOR_1_260114 antikoerper, MGYG_00305 antikoerper, TERG_01248 antikoerper, mogs.L antikoerper, TTHERM_00636930 antikoerper, LOAG_03690 antikoerper, Gcs1 antikoerper, MOGS antikoerper, Mogs antikoerper, mogs antikoerper

Hintergrund: GCS1 cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor in a highly specific manner. Defects in GCS1 are the cause of type IIb congenital disorder of glycosylation (CDGIIb). This syndrome is also known as glucosidase I deficiency and is characterized by marked generalized hypotonia and hypomotility of the neonate, dysmorphic features, including a prominent occiput, short palpebral fissures, retrognathia, high arched palate, generalized edema, and hypoplastic genitalia. Symptoms include hepatomegaly, hypoventilation, feeding problems and seizures. The clinical course is progressive and survival is at most a few months.Synonyms: Mannosyl-oligosaccharide glucosidase, Processing A-glucosidase I

Molekulargewicht: 91840 Da

Gen-ID: 7841, 5874

UniProt: Q13724

Pathways: SARS-CoV-2 Protein Interaktom