ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (C-Term) Antikörper

Antigen: ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4)

Synonyme: ADMP-1, ADAMTS-2, ADAMTS-4, KIAA0688, KIAA0366, ADAM-TS4, mKIAA0688, 3830423K05, ADAMTS4, DKFZp469J0817, AAC2, PNAT, NPI, PCINP, PCPNI, hPCPNI, ADAM-TS2, ADAMTS-3, TTP, VWFCP, C9orf8, vWF-CP, FLJ42993, MGC118899, MGC118900, DKFZp434C2322, ADMP-2, ADAMTS11, FLJ36738, ASMP-2, ADAMTS1, ADAM-TS5, AI481094, 9530092O11Rik, PWTSR, THSD2, CRISTIN1, FLJ14440, AW743315, 1810011L16Rik, 8430403M15Rik, E030027K14Rik, FLJ16042, AU015154, 4831407I23Rik, D230034E10Rik, Gm710, ADAMTS5, ADAMTS13, ADAMTS-11

Epitope: C-Term

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN356434

Produktbeschreibung

Produktmerkmale: Synonyms: ADAMTS-4, ADAM-TS4, Aggrecanase-1, ADMP1, ADMP-1, KIAA0688, A disintegrin andmetalloproteinase with thrombospondin motifs 4

Weitere Bezeichnung: ADAMTS4

Swiss-Prot: O75173

Immunogen: Synthetic peptide corresponding to C-terminal domain of human ADAMTS4 - KLHconjugated. Remarks: Rat Identity: 29%Rat Similarity: 41%

Kreuzreaktivität: Human

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: ADAMTS4, also known as aggrecanase-1, is a Metallopeptidase M12B type protease that isresponsible for degradation of the articular cartilage protein aggrecan and the brainextracellular matrix proteoglycan brevican. The ADAMTS4 protein contains a signalsequence, a propeptide domain, a catalytic domain, a disintegrin-like motif, and aC-terminal domain with a thrombospondin (TSP) type 1 motif. ADAMTS4 has beenimplicated in inflammatory joint diseases, and it also may be a factor in the progression ofglioma and Alzheimer's disease.

Spezifität: This antibody reacts with C-terminal domain of ADAMTS4. Species: Human. Others not tested.

Synonyme: ADMP-1, ADAMTS-2, ADAMTS-4, KIAA0688, KIAA0366, ADAM-TS4, mKIAA0688, 3830423K05, ADAMTS4, DKFZp469J0817, AAC2, PNAT, NPI, PCINP, PCPNI, hPCPNI, ADAM-TS2, ADAMTS-3, TTP, VWFCP, C9orf8, vWF-CP, FLJ42993, MGC118899, MGC118900, DKFZp434C2322, ADMP-2, ADAMTS11, FLJ36738, ASMP-2, ADAMTS1, ADAM-TS5, AI481094, 9530092O11Rik, PWTSR, THSD2, CRISTIN1, FLJ14440, AW743315, 1810011L16Rik, 8430403M15Rik, E030027K14Rik, FLJ16042, AU015154, 4831407I23Rik, D230034E10Rik, Gm710, ADAMTS5, ADAMTS13, ADAMTS-11

Anwendungen

Applikationshinweise: Immunohistochemistry on Paraffin Embedded Tissues: 20 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Konzentration: 1.0 mg/ml

Reinigung: Aff - Purified

Buffer: PBS containing 0.09% Sodium Azide as preservative.

Lagerung: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Beschränkungen: Nur für Forschungszwecke einsetzbar