PTP4A3 Antikörper

Produktnummer ABIN356421

Produktdetails anti-PTP4A3 Antikörper

Target: PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PTP4A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody is specific to PRL3.

Produktmerkmale: Synonyms: PRL-3, PRL-R, Protein tyrosine phosphatase type IVA 3, Protein-tyrosine phosphatase 4a3,Protein-tyrosine phosphatase of regenerating liver 3

Aufreinigung: Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This monoclonal antibody is generated from mice immunized with a recombinant protein.

Klon: 111AT714

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu PTP4A3

Target: PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))

Andere Bezeichnung: PRL3 / PTP4A3 (PTP4A3 Produkte)

Synonyme: PRL-3 antikoerper, PRL-R antikoerper, PRL3 antikoerper, wu:fc54b05 antikoerper, wu:fv52d11 antikoerper, zgc:77109 antikoerper, prl-3 antikoerper, prl3 antikoerper, ptpcaax3 antikoerper, PTP4A3 antikoerper, AV088979 antikoerper, Prl-3 antikoerper, pPtp4a3 antikoerper, protein tyrosine phosphatase type IVA, member 3 antikoerper, protein tyrosine phosphatase type IVA, member 3 L homeolog antikoerper, protein tyrosine phosphatase 4a3 antikoerper, PTP4A3 antikoerper, ptp4a3 antikoerper, ptp4a3.L antikoerper, Ptp4a3 antikoerper

Hintergrund: PRL3 (PTP4A3) belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation.Synonyms: PRL-3, PRL-R, Protein tyrosine phosphatase type IVA 3, Protein-tyrosine phosphatase 4a3, Protein-tyrosine phosphatase of regenerating liver 3

Gen-ID: 100131062

UniProt: O75365