MDS1 and EVI1 Complex Locus (MECOM) (N-Term) Antikörper

Details zu Produkt Nr. ABIN356376, Anbieter: Anmelden zum Anzeigen
Antigen
  • evi1
  • im:7140716
  • prdm3
  • EVI1
  • AML1-EVI-1
  • MDS1
  • MDS1-EVI1
  • PRDM3
  • D630039M04Rik
  • Evi-1
  • Evi1
  • Jbo
  • Mds
  • Mds1
  • Mds1-Evi1
  • Prdm3
  • Znfpr1b1
  • AML1
  • AMLCR1
  • CBFA2
  • EVI-1
  • PEBP2aB
  • MDS1 and EVI1 complex locus
  • runt-related transcription factor 1
  • mecom
  • MECOM
  • LOC100343228
  • Mecom
  • RUNX1
Epitop
N-Term
28
17
17
15
9
5
5
4
4
3
3
2
2
2
1
1
1
1
1
Reaktivität
Human, Maus
105
33
9
4
4
3
3
2
1
1
1
Wirt
Maus
72
30
15
Klonalität (Klon)
Monoklonal ()
Konjugat
Unkonjugiert
6
6
6
6
6
6
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
104
65
11
5
3
2
1
1
1
1
Optionen
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Immunogen This antibody was raised using purified recombinant GST fusion protein encoding theN-terminal part of human PRDM3.
Klon 47AT612-84-88
Isotyp IgG1
Spezifität This antibody is specific to PRDM3.
Produktmerkmale Synonyms: Myelodysplasia syndrome 1, Myelodysplasia syndrome-associated protein 1
Reinigung Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Andere Bezeichnung MDS1 (MECOM Antibody Abstract)
Hintergrund Similar to acetylation and phosphorylation, histone methylation at the N-terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. MDS1, first identified as part of a fusion transcript resulting from the t(3,21)(q26,q22), encodes a small protein of unknown function. EVI1 encodes a zinc finger protein inappropriately overexpressed by chromosomal rearrangements. EVI1 and MDS1 are unusual in that they can either encode separate proteins, or they can be expressed as a fusion protein MDS1/EVI1. EVI1 and MDS1/EVI1 have opposite functions as transcription factors.Synonyms: Myelodysplasia syndrome 1, Myelodysplasia syndrome-associated protein 1
Gen-ID 2122
UniProt Q13465
Applikationshinweise ELISA: 1/1,000. Western blotting: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Haltbarkeit 12 months
Bilder des Herstellers
Western Blotting (WB) image for anti-MDS1 and EVI1 Complex Locus (MECOM) (N-Term) Antikörper (ABIN356376) anti-MDS1 and EVI1 Complex Locus (MECOM) (N-Term) antibody