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Cytokeratin 1 Antikörper (pan)

KRT1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Huhn, Affe, Schwein IHC (p), IF, IHC (fro) Wirt: Maus Monoclonal AE1-AE3 unconjugated
Produktnummer ABIN356301
  • Target Alle Cytokeratin 1 (KRT1) Antikörper anzeigen
    Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
    Bindungsspezifität
    • 21
    • 16
    • 16
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pan
    Reaktivität
    • 97
    • 57
    • 43
    • 24
    • 16
    • 13
    • 9
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Kaninchen, Huhn, Affe, Schwein
    Wirt
    • 77
    • 43
    • 1
    Maus
    Klonalität
    • 70
    • 51
    Monoklonal
    Konjugat
    • 50
    • 15
    • 10
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser Cytokeratin 1 Antikörper ist unkonjugiert
    Applikation
    • 82
    • 55
    • 33
    • 30
    • 27
    • 27
    • 26
    • 19
    • 17
    • 14
    • 13
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    AE 1/AE3 represents an excellent marker for distinguishing carcinomas from non-epithelial tumors, reacts with all epithelium-derived tumors and their neoplasms. Decorates the majority of type I and type II keratins (formerly also designated cytokeratins). This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas. This antibody AE 1/AE 3 recognizes Low Molecular Weight Cytokeratins (CK 10 (56.5), CK14 (50), CK15 (50), CK16 (48) and CK19 (40) of the acidic family and CK1 (67), CK2 (65.5), CK3 (64), CK4 (59), CK5 (58) CK6 (56) and CK8 (52.5).
    Cellular Localization: Cytoplasmic.Cellular Localization:
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Monkey, Bovine, Porcine, Rat, Mouse, Rabbit and Chicken.
    Produktmerkmale
    Synonyms: pan Keratin, Cytokeratin Pan-reactive
    Aufreinigung
    Protein A Chromatography.
    Immunogen
    Human epidermal keratin. Remarks: Molecular weight of antigen: CK1 (67), CK2 (65. 5), CK3 (64), CK4 (59), CK5 (58)CK6 (56) CK8 (52. 5). + CK1 (67), CK2 (65. 5), CK3 (64), CK4 (59), CK5 (58) CK6 (56) CK8 (52. 5).
    Klon
    AE1-AE3
    Isotyp
    IgG1
    Top Product
    Discover our top product KRT1 Primärantikörper
  • Applikationshinweise
    Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears). For IHC dilute concentrated antibody at 1/50-1/100, use streptavidinapprox. biotin system orpolymer system, incubate 30 minutes at room temperature. For FFPE tissue sections antigen retriever like trypsin is required. Recommended Positive Control: Human skin, lung ca.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.2 mg/mL
    Buffer
    PBS, pH 7.4, 0.05 % Sodium Azide, 1 % BSA
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.
    Haltbarkeit
    12 months
  • Target
    Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
    Andere Bezeichnung
    Cytokeratin (KRT1 Produkte)
    Synonyme
    CK1 antikoerper, EHK antikoerper, EHK1 antikoerper, EPPK antikoerper, K1 antikoerper, KRT1A antikoerper, NEPPK antikoerper, Krt-2.1 antikoerper, Krt2-1 antikoerper, Krt86 antikoerper, KRT1 antikoerper, Kb1 antikoerper, KER1 antikoerper, CK-1 antikoerper, Keratin-1 antikoerper, keratin 1 antikoerper, KRT1 antikoerper, Krt1 antikoerper
    Hintergrund
    Cytokeratins are intermediate filament keratins found in the intracytoplasmic cytoskeleton of epithelial tissue There are two types of Cytokeratins: the low weight, acidic type I cytokeratins and the high weight, basic or neutral type II. Cytokeratins are usually found in pairs comprising a type I Cytokeratin and a type II cytokeratin. The high molecular weight cytokeratins, which are the basic or neutral cytokeratins, comprise subtypes CK1(67), CK2(65.5), CK3(64), CK4(59), CK5(58), CK6(56), CK7(54), CK8(52.5) and CK9. The low molecular weight cytokeratins, which are the acidic cytokeratins, comprise subtypes CK10 (56.5), CK12 (56), CK13 (53), CK14 (50), CK16 (48), CK17 (46), CK18 (45), CK19 (48) and CK20 (46).Synonyms: Cytokeratin pan-reactive, pan Keratin
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