RBP4 Antikörper (Retinol Binding Protein 4, Plasma) (AA 19-201)

Details for Product anti-RBP4 Antibody No. ABIN356230, Anbieter: Anmelden zum Anzeigen
Antigen
  • RDCCAS
  • rbp4
  • MGC54038
  • srbp
  • RBP
  • PRBP
  • RBPA
  • Rbp-4
  • fb23c12
  • rbp
  • wu:fb23c12
  • wu:fb58d04
  • wu:fb72b04
  • zgc:86911
  • retinol binding protein 4
  • retinol binding protein 4 S homeolog
  • retinol binding protein 4 A, plasma
  • retinol binding protein 4, plasma
  • retinol binding protein 4 L homeolog
  • RBP4
  • rbp4.S
  • rbp4
  • Rbp4
  • RBP4A
  • rbp4.L
Epitop
AA 19-201
57
32
27
14
13
11
9
7
7
6
6
6
6
5
4
4
3
3
3
2
1
1
1
1
1
1
1
1
Reaktivität
Human
425
125
74
30
28
22
14
14
12
11
9
4
2
2
2
2
1
1
1
Wirt
Maus
234
213
40
17
4
2
2
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser RBP4 Antikörper ist unkonjugiert
44
32
19
14
13
9
9
9
9
9
5
5
5
5
5
5
5
4
4
4
4
4
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
352
341
97
65
58
53
47
25
19
18
11
7
5
5
5
3
2
2
2
2
1
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Recombinant human RBP4 (19-201 aa) purified from E. coli
Klon AT2B4
Isotyp IgG1
Spezifität The antibody recognizes human RBP4. Other species not tested.
Produktmerkmale Synonyms: RBP-4, Retinol-binding protein 4, Plasma retinol-binding protein, PRBP, RBP
Reinigung Protein-G affinity chromatography
Andere Bezeichnung RBP4 (RBP4 Antibody Abstract)
Hintergrund Retinol binding protein 4(RBP4) belongs to the lipocalin family and is the specific carrier for retinol in the blood. This protein was found to be expressed and secreted by adipose tissue, and was strongly associated with insulin resistance. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli.Synonyms: PRBP, Plasma retinol-binding protein, RBP, RBP-4, Retinol-binding protein 4
Gen-ID 5950
UniProt P02753
Forschungsgebiet Cardiovascular, Atherosclerosis, Metabolism, Hormones, Cytokines
Pathways Regulatorische RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
Applikationshinweise ELISA. Western blot (1: 500 - 1: 1,000). Immunohistochemistry on paraffin-embedded tissues (1: 25-1: 50).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1.0 mg/mL
Buffer PBS, pH 7.4, containing 0.09 % sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Haltbarkeit 12 months
Bilder des Herstellers
Western Blotting (WB) image for anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) antibody (ABIN356230) anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) antibody
Immunohistochemistry (IHC) image for anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) antibody (ABIN356230) anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) antibody (Image 2)
Western Blotting (WB) image for anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) antibody (ABIN356230) anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) antibody (Image 3)
Immunohistochemistry (IHC) image for anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) antibody (ABIN356230) anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) antibody (Image 4)
Allgemeine Veröffentlichungen Yao-Borengasser, Varma, Bodles, Rasouli, Phanavanh, Lee, Starks, Kern, Spencer, Rashidi, McGehee, Fried, Kern: "Retinol binding protein 4 expression in humans: relationship to insulin resistance, inflammation, and response to pioglitazone." in: The Journal of clinical endocrinology and metabolism, Vol. 92, Issue 7, pp. 2590-7, 2007 (PubMed).

McTernan, Kumar: "Editorial: Retinol binding protein 4 and pathogenesis of diabetes." in: The Journal of clinical endocrinology and metabolism, Vol. 92, Issue 7, pp. 2430-2, 2007 (PubMed).

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