STEAP1 (C-Term) Antikörper

Antigen: STEAP1 (C-Term)

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB), Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN351550

Produktbeschreibung

Swiss-Prot: Q9UHE8

Immunogen: Synthetic peptide, An 18 amino acid peptide located near the c-terminal region of human STEAP1.

Beschreibung: Gene: STEAP1, Standard Gene Symbol: STEAP1, Synonyms: STEAP1, MGC19484, PRSS24, Six transmembrane epithelial antigen of the prostate, STEAP

Spezifität: Recognizes STEAP1 (six transmembrane epithelial antigen of the prostate), a 39kD protein which is a member of a family of cell surface serpentine transmembrane antigens of the prostate. STEAP1 is predominantly expressed in human prostate and is up-regulated in several cancer lines including prostate, ovarian, cervical, breast, testicular, bladder, colon and Ewing sarcoma. It is significantly expressed at cell-cell junctions and has been shown to be a target of human CD8 T cells. This indicates that it could be used as a potential target for cancer immunotherapy. This antibody does not cross-react with other STEAP-proteins Predicted Reactivities: Mouse (Murine),Rat (Rattus).

Anwendungen

Applikationshinweise: IHC-P (5 µg/ml), WB (1 - 2 µg/ml)

Konzentration: 1 mg/ml

Reinigung: Affinity Chromatography

Buffer: PBS, 0.02% sodium azide.

Lagerung: Long term: -20°C, Short term: +4°C

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Human Lung, Bronchiole (formalin-fixed, paraffin-embedded) stained with STEAP1 antibody ABIN351550 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen.