Xenopus TRPN1 (NompC, Putative Transient Receptor Potential Channel) Antikörper

Antigen: Xenopus TRPN1 (NompC, Putative Transient Receptor Potential Channel)

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Xenopus laevis

Applikation: Immunhistochemie (IHC), Western Blot (WB)

Produktnummer: ABIN351232

Produktbeschreibung

Weitere Bezeichnung: xenopusTRPN1 (nompC, Putative transient receptor potential channel)

Swiss-Prot: Q6RI86

Immunogen: A synthetic peptide as a part of xenopus TRPN1 (nompC, Putative transient receptor potential channel) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Beschreibung: FUNCTION: May function as an ion-channel regulator. May function with PKD2L1 as heteromeric taste channels. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in a subset of taste receptor cells distinct from those involved in bitter, sweet and umami taste. Expressed in circumvallate and foliate taste buds, but not in surrounding non-gustatory lingual epithelium cells. Expressed in testis. Also known as: Putative transient receptor potential channel, nompC.

Spezifität: Appears to be specific for TRPN1.

Anwendungen

Applikationshinweise: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.

Reinheit: whole serum

Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Shin, Adams, Paukert et al.: "Xenopus TRPN1 (NOMPC) localizes to microtubule-based cilia in epithelial cells, including inner-ear hair cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 35, pp. 12572-7, 2005 (PubMed).