TRPC1 Antikörper (Extracellular Loop)

Produktnummer ABIN351118

Produktdetails anti-TRPC1 Antikörper

Target: TRPC1 (Transient Receptor Potential Cation Channel, Subfamily C, Member 1 (TRPC1))

Bindungsspezifität: AA 500-540, Extracellular Loop

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRPC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: Specific for TRPC1.

Immunogen: A synthetic peptide from aa region 500-540 of the 2d extracellular loop of human TRPC1 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: A concentration of 10-50 µg/ml is recommended.
The optimal concentration should be determined by the end user.
Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Handhabung: Avoid freeze and thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu TRPC1

Target: TRPC1 (Transient Receptor Potential Cation Channel, Subfamily C, Member 1 (TRPC1))

Andere Bezeichnung: TRPC1 (TRPC1 Produkte)

Synonyme: HTRP-1 antikoerper, TRP1 antikoerper, Trrp1 antikoerper, xtrpc1 antikoerper, Mtrp1 antikoerper, Trp1 antikoerper, Trpc1 antikoerper, transient receptor potential cation channel subfamily C member 1 antikoerper, transient receptor potential cation channel, subfamily C, member 1 antikoerper, transient receptor potential cation channel, subfamily C, member 1 L homeolog antikoerper, TRPC1 antikoerper, Trpc1 antikoerper, trpc1.L antikoerper, trpc1 antikoerper

Hintergrund: Function: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.
Subunit: Interacts with TRPC3. Interacts with ITPR3.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Seems to be ubiquitous. Also known as: Short transient receptor potential channel 1, TrpC1, TRP-1 protein, Trp1, Trrp1, Trpc1 transient receptor potential cation channel, subfamily C, member 1, Mtrp1, Trp-related protein 1.