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RHOB Antikörper

RHOB Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Schaf Polyclonal unconjugated
Produktnummer ABIN350804
  • Target Alle RHOB Antikörper anzeigen
    RHOB (Ras Homolog Gene Family, Member B (RHOB))
    Reaktivität
    • 44
    • 18
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 44
    • 1
    Schaf
    Klonalität
    • 44
    • 1
    Polyklonal
    Konjugat
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RHOB Antikörper ist unkonjugiert
    Applikation
    • 18
    • 13
    • 13
    • 13
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    Specific for RhOB.
    Kreuzreaktivität
    Human, Maus, Ratte
    Kreuzreaktivität (Details)
    Other species not yet tested.
    Aufreinigung
    IgG
    Immunogen
    A synthetic peptide as a part of human, rat, mouse Rho-related GTP-binding protein RhoB (ARH6, ARHB, H6) conjugated to an immunogenic carrier protein was used as the immunogen.
    Isotyp
    IgG
    Top Product
    Discover our top product RHOB Primärantikörper
  • Applikationshinweise
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    Handhabung
    Avoid freeze and thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Haltbarkeit
    12 months
  • Target
    RHOB (Ras Homolog Gene Family, Member B (RHOB))
    Andere Bezeichnung
    RhoB (RHOB Produkte)
    Synonyme
    ARH6 antikoerper, ARHB antikoerper, MST081 antikoerper, MSTP081 antikoerper, RHOH6 antikoerper, AA017882 antikoerper, Arh6 antikoerper, Arhb antikoerper, RHO antikoerper, arha antikoerper, rhoa antikoerper, wu:fj42e08 antikoerper, zgc:92206 antikoerper, rhob antikoerper, xrhob antikoerper, ras homolog family member B antikoerper, ras homolog gene family, member Ab antikoerper, ras homolog family member B S homeolog antikoerper, RHOB antikoerper, Rhob antikoerper, rhoab antikoerper, rhob.S antikoerper
    Hintergrund
    FUNCTION: Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. SUBUNIT: Binds ROCK1 and ROCK2. Also binds PKN1/PRK1. Interacts with ARHGEF3 and AKAP13. Interacts with RTKN. SUBCELLULAR LOCATION: Late endosome membrane, Lipid-anchor. Cell membrane, Lipid-anchor. Nucleus. Note: Late endosomal membrane (geranylgeranylated form). Plasma membrane (farnesylated form). Also detected at the nuclear margin and in the nucleus. INDUCTION: By UV irradiation, N-methyl-N-nitrosourea, cisplatin, cyclohexamide and serum stimulation.,Rho Family,H6, ARH6, ARHB, RHOH6, MST081, MSTP081
    UniProt
    P62745
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