Ras-Related Protein Rab-5C (Rab5c) (internal) Antikörper

Antigen: Ras-Related Protein Rab-5C (Rab5c)

Synonyme: Rabl, AI326010

Epitope: internal

Klonalität: Polyklonal

Wirt: Kaninchen

Applikation: Immunhistochemie (IHC), Western Blot (WB)

Produktnummer: ABIN350784

Produktbeschreibung

Weitere Bezeichnung: Ras-related protein Rab-5C (RAB5C) (internal region)

Swiss-Prot: P35278

Immunogen: A synthetic peptide from the internal part of Ras-related protein Rab-5C (RAB5C) conjugated to an immunogenic carrier protein has been used as the immunogen. The antigen shares 98% identity with rat.

Format: Lyophilized

Beschreibung: FUNCTION: Protein transport. Probably involved in vesicular traffic. SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane; Lipid-anchor. Melanosome. Also known as: RAB5C.

Spezifität: Appears to be specific for RAB5C.

Anwendungen

Applikationshinweise: IHC, WB. Use at a dilution of 1:300 to 1: 2000. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Reinheit: whole serum

Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Merithew, Hatherly, Dumas et al.: "Structural plasticity of an invariant hydrophobic triad in the switch regions of Rab GTPases is a determinant of effector recognition." in: The Journal of biological chemistry, Vol. 276, Issue 17, pp. 13982-8, 2001 (PubMed).