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Pro BDNF Antikörper

proBDNF Reaktivität: Ratte IHC, WB Wirt: Schaf Polyclonal unconjugated
Produktnummer ABIN350770
  • Target Alle Pro BDNF (proBDNF) Produkte
    Pro BDNF (proBDNF) (Pro-Brain-Derived Neurotrophic Factor (proBDNF))
    Reaktivität
    • 5
    • 4
    • 2
    Ratte
    Wirt
    • 3
    • 2
    • 1
    Schaf
    Klonalität
    • 4
    • 2
    Polyklonal
    Konjugat
    • 5
    • 1
    Dieser Pro BDNF Antikörper ist unkonjugiert
    Applikation
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB)
    Spezifität
    Specific for proBDNF.
    Kreuzreaktivität
    Maus, Ratte
    Kreuzreaktivität (Details)
    Other species not yet tested.
    Aufreinigung
    IgG
    Immunogen
    A synthetic peptide from rat proBDNF conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse and zebrafish and shares 96% identity with human sequence.
    Isotyp
    IgG
  • Applikationshinweise
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
    Handhabung
    Avoid freeze and thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Pro BDNF (proBDNF) (Pro-Brain-Derived Neurotrophic Factor (proBDNF))
    Abstract
    proBDNF Produkte
    Hintergrund
    FUNCTION: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted.,BDNF,Brain-derived neurotrophic factor precursor, proBDNF, pro BDNF
    UniProt
    P23363
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