Polycystic Kidney Disease 2-Like 2 (PKD2L2) (4th cytoplasmic loop) Antikörper

Antigen: Polycystic Kidney Disease 2-Like 2 (PKD2L2)

Synonyme: PKD2L2, MGC133828

Epitope: 4th cytoplasmic loop

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Immunhistochemie (IHC), Western Blot (WB)

Produktnummer: ABIN350749

Produktbeschreibung

Weitere Bezeichnung: polycystic kidney disease 2-like 2 protein (PKD2L2, PK2L2, Polycystin-L2) (4th cytoplasmic loop)

Swiss-Prot: Q9NZM6

Immunogen: A synthetic peptide from the 4th cytoplasmic loop of human Polycystic kidney disease 2-like 2 protein (PKD2L2, PK2L2, Polycystin-L2) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Beschreibung: FUNCTION: May function as a subunit of a cation channel and play a role in fertilization. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. Also known as: PKD2L2, PK2L2, Polycystin-L2.

Spezifität: Appears to be specific for PKD2L2.

Anwendungen

Applikationshinweise: IHC, WB. A dilution of 1 : 300 to 1 : 3000 is recommended. The optimal dilution should be determined by the end user.

Reinheit: whole serum

Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Veldhuisen, Spruit, Dauwerse et al.: "Genes homologous to the autosomal dominant polycystic kidney disease genes (PKD1 and PKD2)." in: European journal of human genetics : EJHG, Vol. 7, Issue 8, pp. 860-72, 2000 (PubMed).

Guo, Schreiber, Weremowicz et al.: "Identification and characterization of a novel polycystin family member, polycystin-L2, in mouse and human: sequence, expression, alternative splicing, and chromosomal localization." in: Genomics, Vol. 64, Issue 3, pp. 241-51, 2000 (PubMed).

Stayner, Zhou: "Polycystin channels and kidney disease." in: Trends in pharmacological sciences, Vol. 22, Issue 11, pp. 543-6, 2001 (PubMed).