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Rho-related GTP-binding protein Antikörper

RhO (pan) Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Schaf Polyclonal unconjugated
Produktnummer ABIN350723
  • Target Alle Rho-related GTP-binding protein (RhO (pan)) Antikörper anzeigen
    Rho-related GTP-binding protein (RhO (pan))
    Reaktivität
    • 19
    • 9
    • 9
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 25
    • 7
    Schaf
    Klonalität
    • 23
    • 9
    Polyklonal
    Konjugat
    • 23
    • 3
    • 2
    • 2
    • 1
    • 1
    Dieser Rho-related GTP-binding protein Antikörper ist unkonjugiert
    Applikation
    • 24
    • 19
    • 14
    • 5
    • 5
    • 4
    • 4
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    Specific for RhO family.
    Immunogen
    A synthetic peptide as a part of human/rat/mouse/chicken/dog/frog (and more species) Rho-related GTP-binding proteins (RhOA, RhOB, RhOC, RhOF, RhOQ) and RAC1, RAC2, RAC3 and CDC42 conjugated to an immunogenic carrier protein was used as the immunogen.
    Isotyp
    IgG
    Top Product
    Discover our top product RhO (pan) Primärantikörper
  • Applikationshinweise
    A concentration of 10-50 µg/ml is recommended.
    The optimal concentration should be determined by the end user.
    Not yet tested in other applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
    Handhabung
    Avoid freeze and thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Rho-related GTP-binding protein (RhO (pan))
    Abstract
    RhO (pan) Produkte
    Substanzklasse
    Chemical
    Hintergrund
    The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Also known as: Rho-related GTP-binding protein RhOA, RhOB, RhOC, RhOF, RhOQ, RAC1, RAC2, RAC3, CDC42.
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