Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 (P2RX6) (cytoplasmic domain) Antikörper

Antigen: Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 (P2RX6)

Synonyme: P2x6, P2xm, P2rxl1, MGC141601, P2RX6, P2RXL1

Epitope: cytoplasmic domain

Klonalität: Polyklonal

Wirt: Kaninchen

Applikation: Immunhistochemie (IHC), Western Blot (WB)

Produktnummer: ABIN350703

Produktbeschreibung

Weitere Bezeichnung: P2X6 (P2RX6, P2X purinoceptor 6, ATP receptor, P2RXL1, P2XM) (cytoplasmic domain)

Swiss-Prot: O54803

Immunogen: A synthetic peptide from the cytoplasmic domain of mouse P2X6 (P2RX6, P2X purinoceptor 6, ATP receptor, P2RXL1) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat and shares 86% identity with human sequence.

Format: Lyophilized

Beschreibung: Function: Receptor for ATP that acts as a ligand gated ion channel Subcellular location: Membrane; Multi-pass membrane protein. Tissue specificity: Expressed predominantly in skeletal muscle. Also known as: P2RX6, P2X purinoceptor 6, ATP receptor, Purinergic receptor, P2RXL1, P2XM.

Spezifität: Appears to be specific for P2RX6.

Anwendungen

Applikationshinweise: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Reinheit: whole serum

Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Urano, Nishimori, Han et al.: "Cloning of P2XM, a novel human P2X receptor gene regulated by p53." in: Cancer research, Vol. 57, Issue 15, pp. 3281-7, 1997 (PubMed).

Nawa, Urano, Tokino et al.: "Cloning and characterization of the murine P2XM receptor gene." in: Journal of human genetics, Vol. 43, Issue 4, pp. 262-7, 1999 (PubMed).

Maguire, Wynne, Harney et al.: "Identification of the phosphotyrosine proteome from thrombin activated platelets." in: Proteomics, Vol. 2, Issue 6, pp. 642-8, 2002 (PubMed).

Collins, Wright, Edwards et al.: "A genome annotation-driven approach to cloning the human ORFeome." in: Genome biology, Vol. 5, Issue 10, pp. R84, 2004 (PubMed).