Purinergic Receptor P2X, Ligand-Gated Ion Channel, 5 (P2RX5) (cytoplasmic domain) Antikörper

Antigen: Purinergic Receptor P2X, Ligand-Gated Ion Channel, 5 (P2RX5)

Synonyme: P2X5, LRH-1, P2X5R, MGC47755, P2x5, P2RX5

Epitope: cytoplasmic domain

Klonalität: Polyklonal

Wirt: Kaninchen

Applikation: Immunhistochemie (IHC), Western Blot (WB)

Produktnummer: ABIN350700

Produktbeschreibung

Weitere Bezeichnung: P2X5 (P2RX5, P2X purinoceptor 5, ATP receptor) (cytoplasmic domain)

Swiss-Prot: P51578

Immunogen: A synthetic peptide from the cytoplasmic domain of rat P2X5 (P2RX5, P2X purinoceptor 5, ATP receptor) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen shares 90% identity with mouse sequence.

Format: Lyophilized

Beschreibung: Function: Receptor for ATP that acts as a ligand gated ion channel. Subcellular location: Membrane; Multi-pass membrane protein. Tissue specificity: Expressed at high levels in brain and immune system. Also known as: P2X5, P2RX5, P2X purinoceptor 5, ATP receptor, Purinergic receptor.

Spezifität: Appears to be specific for P2RX5.

Anwendungen

Applikationshinweise: IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Reinheit: whole serum

Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Lue, Paquet, Nouel et al.: "Primary structure and expression of a naturally truncated human P2X ATP receptor subunit from brain and immune system." in: FEBS letters, Vol. 418, Issue 1-2, pp. 195-9, 1998 (PubMed).

Touchman, Anikster, Dietrich et al.: "The genomic region encompassing the nephropathic cystinosis gene (CTNS): complete sequencing of a 200-kb segment and discovery of a novel gene within the common cystinosis-causing deletion." in: Genome research, Vol. 10, Issue 2, pp. 165-73, 2000 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Yu, Zhu, Chan et al.: "Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra." in: Journal of proteome research, Vol. 6, Issue 11, pp. 4150-62, 2007 (PubMed).