olfactory receptor (OR1S1 and OR1S2; OR11-231, OR11-232) Antikörper

Antigen: olfactory receptor (OR1S1 and OR1S2; OR11-231, OR11-232)

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Immunhistochemie (IHC), Western Blot (WB)

Produktnummer: ABIN350627

Produktbeschreibung

Swiss-Prot: Q8NH92

Immunogen: A synthetic peptide as a part of human olfactory receptor OR1S1 and OR1S2 (OR11-231, OR11-232) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Beschreibung: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. Theolfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. Theolfactory receptor gene family is the largest in the genome. The nomenclature assigned to theolfactory receptor genes and proteins for this organism is independent of other organisms. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein Useful Links <||a href="http://bioportal.weizmann.ac.il/HORDE/links.html"> The Humanolfactory Data Exploratorium: HORDE <||/a> <||a href="http://senselab.med.yale.edu/senselab/ordb/">olfactory Receptor Data Base: ORDB <||/a><||a href="http://www.enzim.hu/hmmtop1.1/server/submit.html"> <||/a> Also known as:olfactory receptor, family 1, subfamily S, member 1;olfactory receptor, family 1, subfamily S, member 2,olfactory receptor 1S1,olfactory receptor 1S2, OR11-231, OR11-232.

Spezifität: Appears to be specific for Olfactory receptor OR1S1, OR1S2.

Anwendungen

Applikationshinweise: IHC, WB. A dilution of 1 : 300 to 1 : 4000 is recommended. The optimal dilution should be determined by the end user.

Reinheit: whole serum

Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Fuchs, Malecova, Linhart et al.: "DEFOG: a practical scheme for deciphering families of genes." in: Genomics, Vol. 80, Issue 3, pp. 295-302, 2002 (PubMed).

Malnic, Godfrey, Buck: "The human olfactory receptor gene family." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 8, pp. 2584-9, 2004 (PubMed).