olfactory receptor (MOR4-1 or Olfr620MOR4-2P or Olfr624) Antikörper

Antigen: olfactory receptor (MOR4-1 or Olfr620MOR4-2P or Olfr624)

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Maus

Applikation: Immunhistochemie (IHC), Western Blot (WB)

Produktnummer: ABIN350593

Produktbeschreibung

Swiss-Prot: Q8VG77

Immunogen: A synthetic peptide as a part of mouse olfactory receptor family 4, subfamily 1 and 2P (MOR4-1 and MOR4-2P) conjugated to immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Beschreibung: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. Theolfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein SIMILARITY: Belongs to the G-protein coupled receptor 1 family Useful Links <||a href="http://bioportal.weizmann.ac.il/HORDE/links.html" > The Humanolfactory Data Exploratorium: HORDE <||/a> <||a href="http://senselab.med.yale.edu/senselab/ordb/" >olfactory Receptor Data Base: ORDB <||/a> <||a href="http://www.enzim.hu/hmmtop1.1/server/submit.html" >transmembrane Analysis: TM analysis<||/a> Also known as:olfactory receptors Olfr620 (MOR4-1) and Olfr624 (MOR4-2P).

Spezifität: Appears to be specific for MOR4-1 and MOR4-2P.

Anwendungen

Applikationshinweise: IHC, WB. A dilution of 1 : 300 to 1 : 4000 is recommended. The optimal dilution should be determined by the end user.

Reinheit: whole serum

Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Zhang, Firestein: "The olfactory receptor gene superfamily of the mouse." in: Nature neuroscience, Vol. 5, Issue 2, pp. 124-33, 2002 (PubMed).

Young, Friedman, Williams et al.: "Different evolutionary processes shaped the mouse and human olfactory receptor gene families." in: Human molecular genetics, Vol. 11, Issue 5, pp. 535-46, 2002 (PubMed).

Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Young, Shykind, Lane et al.: "Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels." in: Genome biology, Vol. 4, Issue 11, pp. R71, 2003 (PubMed).