Mucolipin 2 (MCOLN2) (C-Term) Antikörper

Antigen: Mucolipin 2 (MCOLN2)

Synonyme: TRPML2, TRP-ML2, FLJ36691, C86638, AI549968, 3300002C04Rik, MGC124828, MGC55310, zgc:55310, MGC80330

Epitope: C-Term

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Maus

Applikation: Immunhistochemie (IHC), Western Blot (WB)

Produktnummer: ABIN350487

Produktbeschreibung

Weitere Bezeichnung: Mucolipin 2 (Mcoln2, MCLN2,TRPML2) (c-terminal region)

Swiss-Prot: Q8K595

Immunogen: A synthetic peptide from the c-terminal region of mouse Mucolipin 2 conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Beschreibung: Mucolipins constitute a family of cation channel proteins with homologs in mouse, Drosophila, and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein Also known as: TRPML2,Mucolipin-2, MCOLN2,Mucolipin 2, TRPML2, TRP-ML2.

Spezifität: Appears to be specific for Mucolipin 2.

Anwendungen

Applikationshinweise: IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Reinheit: whole serum

Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Di Palma, Belyantseva, Kim et al.: "Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 23, pp. 14994-9, 2002 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).