Meteorin, Glial Cell Differentiation Regulator (METRN) (internal) Antikörper

Antigen: Meteorin, Glial Cell Differentiation Regulator (METRN)

Synonyme: MGC2601, C16orf23, c380A1.2, Hyrac, 1810034B16Rik, RGD1306222, mtrn, zgc:92132, wu:fb81a08, METRN

Epitope: internal

Klonalität: Polyklonal

Wirt: Kaninchen

Applikation: Immunhistochemie (IHC), Western Blot (WB)

Produktnummer: ABIN350460

Produktbeschreibung

Weitere Bezeichnung: Meteorin (METRN) (internal region)

Swiss-Prot: Q9UJH8

Immunogen: A synthetic peptide from the internal region of human Meteorin (METRN) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Beschreibung: Function: Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia. Subcellular location: Secreted Also known as: Meteorin, METRN.

Spezifität: Appears to be specific for Meteorin.

Anwendungen

Applikationshinweise: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Reinheit: whole serum

Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Daniels, Peden, Lloyd et al.: "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16." in: Human molecular genetics, Vol. 10, Issue 4, pp. 339-52, 2001 (PubMed).

Nishino, Yamashita, Hashiguchi et al.: "Meteorin: a secreted protein that regulates glial cell differentiation and promotes axonal extension." in: The EMBO journal, Vol. 23, Issue 9, pp. 1998-2008, 2004 (PubMed).

Martin, Han, Gordon et al.: "The sequence and analysis of duplication-rich human chromosome 16." in: Nature, Vol. 432, Issue 7020, pp. 988-94, 2004 (PubMed).