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Antikörper
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anti-Homer Homolog 3 (Drosophila) (HOMER3) (internal) Antikörper
Homer Homolog 3 (Drosophila) (HOMER3) (internal) Antikörper
| Antigen |
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| Synonyme |
Vesl-3, HOMER3, MGC55557, VESL3, HOMER-3, AW146114 |
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Epitope
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| Klonalität |
Polyklonal |
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Wirt
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Applikation
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Durchflusszytometrie (FACS) (19), Immunfluoreszenz (IF) (18), Western Blot (WB) (10), ELISA (4), ELISA (Detektionsantikörper) (2), Enzyme Immunoassay (EIA) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunhistochemie (Paraffinschnitte) (IHC (p)) (2), Immunpräzipitation (IP) (2), Dot Blot (Dot) (1), Immunoelectron Microscopy (IEM) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1), Immunhistochemie (IHC) (1)
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| Produktnummer |
ABIN350375 |
| Menge |
100 µl |
| Preis |
317,95 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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HOMER3 (Home3, Vesl-3, Vesl3, Homer-3) (internal region)
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Swiss-Prot
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Q9Z2X5
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Immunogen
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A synthetic peptide from the internal part of rat HOMER3 (Home3, Vesl-3, Vesl3, Homer-3) conjugated to an immunogenic carrier protein was used as the immunogen.
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Format
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Lyophilized
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Beschreibung
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FUNCTION: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors it aids the coupling of surface receptors to intracellular calcium release. SUBUNIT: Encodes coiled-coil structures that mediate homo- and heteromultimerization. SUBCELLULAR LOCATION: Cytoplasm. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Note: Postsynaptic density of neuronal cells. It may interact with group I metabotropic glutamate receptors and regulate their coupling to membrane ion channels. Also known as: Home3, Homer protein homolog 3, VASP/Ena-related gene up-regulated during seizure and LTP 3, Vesl-3, Vesl3.
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Spezifität
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Appears to be specific for Homer3.
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Applikationshinweise
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IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.
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Reinheit
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whole serum
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Lagerung
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Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Homer Homolog 3 (Drosophila) (HOMER3)", Typ "Antikörper" finden
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Wirte
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Kaninchen (26), Maus (2)
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Reaktivitäten
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Human (26), Maus (19), Ratte (Rattus) (17), Hund (16), Huhn (15), Rind (Kuh) (15), Pferd (1), Schwein (1)
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Applikationen
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Durchflusszytometrie (FACS) (19), Immunfluoreszenz (IF) (18), Western Blot (WB) (10), ELISA (4), ELISA (Detektionsantikörper) (2), Enzyme Immunoassay (EIA) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunhistochemie (Paraffinschnitte) (IHC (p)) (2), Immunpräzipitation (IP) (2), Dot Blot (Dot) (1), Immunoelectron Microscopy (IEM) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1), Immunhistochemie (IHC) (1)
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Konjugate
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitope
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Center (1), pThr36 (1)
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Alternativen 
