Histatin 1 (HTN1) (internal) Antikörper

Antigen: Histatin 1 (HTN1)

Synonyme: HIS1

Epitope: internal

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Immunhistochemie (IHC), Western Blot (WB)

Produktnummer: ABIN350373

Produktbeschreibung

Weitere Bezeichnung: Histatin 1 (Histatin-1) (internal region)

Swiss-Prot: P15515

Immunogen: A synthetic peptide from internal region of human Histatin-1 conjugated to an immunogenic carrier protein has been used as the immunogen.

Format: Lyophilized

Beschreibung: FUNCTION: Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. Tissue specificity: Submandibular and parotid glands. Also known as: Histatin-1, Histidine-rich protein 1, HTN1, HIS1.

Spezifität: Appears to be specific for Histatin-1.

Anwendungen

Applikationshinweise: IHC, WB. Use at a dilution of 1:100 to 1: 2000. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Reinheit: whole serum

Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Sugiyama, Ogino, Ogata: "Rapid purification and characterization of histatins (histidine-rich polypeptides) from human whole saliva." in: Archives of oral biology, Vol. 35, Issue 6, pp. 415-9, 1990 (PubMed).

vanderSpek, Wyandt, Skare et al.: "Localization of the genes for histatins to human chromosome 4q13 and tissue distribution of the mRNAs." in: American journal of human genetics, Vol. 45, Issue 3, pp. 381-7, 1989 (PubMed).

Oppenheim, Xu, McMillian et al.: "Histatins, a novel family of histidine-rich proteins in human parotid secretion. Isolation, characterization, primary structure, and fungistatic effects on Candida albicans." in: The Journal of biological chemistry, Vol. 263, Issue 16, pp. 7472-7, 1988 (PubMed).

Oppenheim, Yang, Diamond et al.: "The primary structure and functional characterization of the neutral histidine-rich polypeptide from human parotid secretion." in: The Journal of biological chemistry, Vol. 261, Issue 3, pp. 1177-82, 1986 (PubMed).

Cabras, Fanali, Monteiro et al.: "Tyrosine polysulfation of human salivary histatin 1. A post-translational modification specific of the submandibular gland." in: Journal of proteome research, Vol. 6, Issue 7, pp. 2472-80, 2007 (PubMed).