Pro-Hepcidin (AA 39-59) Antikörper
Reaktivität: Maus
IHC, WB
Wirt: Kaninchen
Polyclonal
unconjugated
(1 reference)-
- Target
- Pro-Hepcidin
- Bindungsspezifität
- AA 39-59
- Reaktivität
- Maus
- Wirt
- Kaninchen
- Klonalität
- Polyklonal
- Applikation
- Immunohistochemistry (IHC), Western Blotting (WB)
- Spezifität
- Specific for Hepcidin.
- Kreuzreaktivität
- Maus
- Kreuzreaktivität (Details)
- Other species not yet tested.
- Aufreinigung
- IgG
- Immunogen
- A synthetic peptide from AA 39-59 of pro region of mouse Hepcidin conjugated to blue carrier protein has been used as the antigen.
- Isotyp
- IgG
-
- Applikationshinweise
- IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
- Handhabung
- Avoid freeze and thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- Haltbarkeit
- 12 months
-
-
: "The kidney hepcidin/ferroportin axis controls iron reabsorption and determines the magnitude of kidney and systemic iron overload." in: Kidney international, Vol. 100, Issue 3, pp. 559-569, (2021) (PubMed).
-
: "The kidney hepcidin/ferroportin axis controls iron reabsorption and determines the magnitude of kidney and systemic iron overload." in: Kidney international, Vol. 100, Issue 3, pp. 559-569, (2021) (PubMed).
-
- Target
- Pro-Hepcidin
- Synonyme
- HAMP antikoerper, hepcidin antikoerper, hepcidin antimicrobial peptide antikoerper, hamp antikoerper, HAMP antikoerper
- Hintergrund
- FUNCTION: Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages. May also have antimicrobial activity. SUBCELLULAR LOCATION: Secreted. Tissue specificity: Highly expressed in the liver and to a much lesser extent in the heart.,Hepcidin,Hepcidin, Liver-expressed antimicrobial peptide, LEAP-1, Putative liver tumor regressor, HAMP, HEPC, LEAP1
- UniProt
- Q9EQ21
-
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