Cofilin Antikörper

Produktnummer ABIN350240

Produktdetails anti-Cofilin Antikörper

Target: Cofilin (CFL1) (Cofilin 1 (CFL1))

Reaktivität: Human

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser Cofilin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: Specific for Cofilin-1.

Kreuzreaktivität: Human, Maus, Ratte

Kreuzreaktivität (Details): Other species not yet tested.

Aufreinigung: IgG

Immunogen: A synthetic peptide from the phospho Y140 & S156 of human Cofilin-1 (Cofilin, non-muscle isoform) conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat, mouse and monkey.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. This antibody may also recognice the unphosphorylated form. Not tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Handhabung: Avoid freeze and thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu Cofilin

Target: Cofilin (CFL1) (Cofilin 1 (CFL1))

Andere Bezeichnung: Cofilin-1 (CFL1 Produkte)

Synonyme: cfl1 antikoerper, xac1 antikoerper, xac2 antikoerper, cfl antikoerper, cb86 antikoerper, sb:cb86 antikoerper, zgc:56501 antikoerper, wu:fb18a04 antikoerper, wu:fk77b03 antikoerper, 12/8 antikoerper, ADF antikoerper, ADF/cofilin antikoerper, Adf antikoerper, CG4254 antikoerper, Cadf antikoerper, D-cof antikoerper, D61 antikoerper, Dmel\\CG4254 antikoerper, T8 antikoerper, Tsr antikoerper, cofilin antikoerper, cofilin/ADF antikoerper, cofilin/actin depolymerizing factor homolog antikoerper, l(2)03101 antikoerper, l(2)k03101 antikoerper, l(2)k05633 antikoerper, l(2)k13409 antikoerper, ntf antikoerper, CFL antikoerper, AA959946 antikoerper, Cof antikoerper, CFL1 antikoerper, cofilin 1 (non-muscle) L homeolog antikoerper, cofilin 1 (non-muscle) antikoerper, cofilin 1 (non-muscle), like antikoerper, cofilin 1 antikoerper, twinstar antikoerper, cofilin antikoerper, cofilin 1, non-muscle antikoerper, Contrafreeloading antikoerper, cfl1.L antikoerper, cfl1 antikoerper, cfl1l antikoerper, CFL1 antikoerper, tsr antikoerper, COF1 antikoerper, TSTA_042790 antikoerper, Cfl1 antikoerper, CFL antikoerper

Hintergrund: FUNCTION: Controls reversibly actin polymerization and depolymerization in a pH -sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. SUBCELLULAR LOCATION: Nucleus matrix. Cytoplasm, cytoskeleton. Note: Almost completely in nucleus in cells exposed to heat shock or 10 % dimethyl sulfoxide. TISSUE SPECIFICITY: Widely distributed in various tissues.,Growth & Development,Cofilin, non-muscle isoform

UniProt: P23528

Pathways: Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events