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Chloride Channel, Voltage-Sensitive 7 (CLCN7) (AA 250-300) Antikörper

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Antigen
Synonyme AA409691, AW538136, ClC-7, D17Wsu51e, CLC-7, CLC7, OPTA2, OPTB4, PPP1R63
Epitop
AA 250-300
(22), (16), (13), (4), (3), (2), (1), (1), (1)
Reaktivität
Human, Maus, Ratte (Rattus)
(47), (16), (12)
Wirt
Kaninchen
(46), (5)
Klonalität
Polyklonal
Konjugat
Unkonjugiert
(2), (2), (2), (2), (2), (2)
Applikation
Immunhistochemie (IHC), Western Blot (WB)
(44), (36), (20), (15), (9), (4), (1), (1), (1)
Pubmed 5 Publikationen vorhanden
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Menge 100 μL
Optionen
Lieferung nach Deutschland ( )
Verfügbarkeit Lieferung in 7 bis 8 Werktagen
Immunogen A synthetic peptide from aa region 250-300 of human CLCN7 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat and mouse.
Spezifität Specific for CLCN7.
Reinigung Whole serum
Andere Bezeichnung CLCN7 (CLCN7 Antibody Abstract)
Hintergrund Function: Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen.
Subcellular location: Lysosome membrane, Multi-pass membrane protein.
Tissue specificity: Brain, testis, muscle and kidney. Also known as: ClC-7, CLCN7, CLC7.
Applikationshinweise A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handhabung Avoid freeze and thaw cycles.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Haltbarkeit 12 months
Allgemeine Veröffentlichungen Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Lam, Tong, Wong et al.: "DNA-based diagnosis of malignant osteopetrosis by whole-genome scan using a single-nucleotide polymorphism microarray: standardization of molecular investigations of genetic diseases due to consanguinity." in: Journal of human genetics, Vol. 52, Issue 1, pp. 98-101, 2006 (PubMed).

Martin, Han, Gordon et al.: "The sequence and analysis of duplication-rich human chromosome 16. ..." in: Nature, Vol. 432, Issue 7020, pp. 988-94, 2004 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Frattini, Pangrazio, Susani et al.: "Chloride channel ClCN7 mutations are responsible for severe recessive, dominant, and intermediate osteopetrosis." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 18, Issue 10, pp. 1740-7, 2003 (PubMed).

Produktnummer ABIN350221
433,02 €
Zzgl. Versandkosten 20,00 € und MWSt

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