Transient Receptor Potential Cation Channel, Subfamily V, Member 3 (TRPV3) (4th cytoplasmic loop) Antikörper

Antigen: Transient Receptor Potential Cation Channel, Subfamily V, Member 3 (TRPV3)

Synonyme: VRL3, Nh, AI644701, MGC124324, MGC124325, 1110036I10Rik, TRPV3, MGC159979

Epitope: 4th cytoplasmic loop

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Huhn

Applikation: Immunhistochemie (IHC), Western Blot (WB)

Produktnummer: ABIN350216

Produktbeschreibung

Weitere Bezeichnung: TRPV3 (Transient receptor potential cation channel subfamily V member 3) (4th cytoplasmic loop)

Swiss-Prot: 118100263

Immunogen: A synthetic peptide from the 4th cytoplasmic loop of chicken TRPV3 (Transient receptor potential cation channel subfamily V member 3) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Beschreibung: FUNCTION: Putative receptor-activated non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. May associate with TRPV1 and may modulate its activity. SUBUNIT: May form a heteromeric channel with TRPV1. Interacts with TRPV1. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in keratinocytes and hair follicles. Also known as: Transient receptor potential cation channel subfamily V member 3.

Spezifität: Appears to be specific for TRPV3.

Anwendungen

Applikationshinweise: IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Reinheit: whole serum

Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Liedtke, Choe, Martui-Renom et al.: "Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor." in: Cell, Vol. 103, Issue 3, pp. 525-35, 2000 (PubMed).