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Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (1st cytoplasmic loop) Antikörper

Antigen

Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8)
Synonyme TRPP8, LTRPC6, MGC2849, CMR1, Trp-p8, LTrpC-6, TRPM8, trpp8, ltrpc6, trpm8b
Epitope
Alternativen

1st cytoplasmic loop
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen
Reaktivität
Applikation
Alternativen Immunhistochemie (IHC), Western Blot (WB)
1 Publikation vorhanden
Produktnummer ABIN350214
Menge 100 µl  (Varianten)
Preis 317,95 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung
Anwendungen Publikationen Alternativen Sekundärantikörper Varianten zurück nach oben

Weitere Bezeichnung TRPM8 (Menthol receptor) (1t cytoplasmic loopl)
Swiss-Prot Q5UKZ3
Immunogen A synthetic peptide from the 1t cytoplasmic loop of chicken TRPM8 (Menthol receptor) conjugated to an immunogenic carrier protein was used as the immunogen.
Format Lyophilized
Beschreibung FUNCTION: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. SUBUNIT: Interacts with TRPC3. Interacts with ITPR3. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Seems to be ubiquitous. Also known as: Menthol receptor.
Spezifität Appears to be specific for TRPM8.

Anwendungen
Publikationen Alternativen Sekundärantikörper Varianten zurück nach oben

Applikationshinweise IHC, WB. A dilution of 1 : 300 to 1 : 3000 is recommended. The optimal dilution should be determined by the end user.
Reinheit whole serum
Lagerung Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Beschränkungen Nur für Forschungszwecke einsetzbar

Publikationen
Anwendungen Alternativen Sekundärantikörper Varianten zurück nach oben

Publikationen Chuang, Neuhausser, Julius: "The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel." in: Neuron, Vol. 43, Issue 6, pp. 859-69, 2004 (PubMed).

Alternativen
Anwendungen Publikationen Sekundärantikörper Varianten zurück nach oben

Alternativen zu Antigen "Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8)", Typ "Antikörper" finden
Wirte Kaninchen (42), Ziege (4), Schaf (3)
Reaktivitäten Human (33), Ratte (Rattus) (11), Maus (8), Krokodil (3), Huhn (1), Rind (Kuh) (1), Hund (1), Kaninchen (1)
Applikationen Western Blot (WB) (41), Immunhistochemie (IHC) (19), Enzyme Immunoassay (EIA) (9), Immunhistochemie (Paraffinschnitte) (IHC (p)) (7), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (6), ELISA (5), Dot Blot (Dot) (1), Immunfluoreszenz (IF) (1)
Epitope 1st cytoplasmic loop (5), 4th cytoplasmic loop (3), C-Term (3), 3rd extracellular loop (2), Center (2), C-Term C940 (1), Center R536 (1), internal (1)