Calcium Channel, Voltage-Dependent, gamma Subunit 3 (CACNG3) (N-Term) Antikörper

Antigen: Calcium Channel, Voltage-Dependent, gamma Subunit 3 (CACNG3)

Synonyme: Cacng2, CACNG3, DKFZp459K1027

Epitope: N-Term

Klonalität: Polyklonal

Wirt: Kaninchen

Applikation: Immunhistochemie (IHC), Western Blot (WB)

Produktnummer: ABIN350164

Produktbeschreibung

Weitere Bezeichnung: CACNG3 (n-terminal region)

Swiss-Prot: O60359

Immunogen: A synthetic peptide from the n-terminal region of human CACNG3 conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat, mouse.

Format: Lyophilized

Beschreibung: FUNCTION: Thought to stabilize the calcium channel in an inactivated (closed) state. Involvement in disease: Candidate gene for a familial infantile convulsive disorder with paroxysomal choreoathetosis. Subcellular location: Membrane; Single-pass type I membrane protein Also known as: Voltage-dependent calcium channel gamma-3 subunit, Neuronal voltage-gated calcium channel gamma-3 subunit.

Spezifität: Appears to be specific for CACNG3.

Anwendungen

Applikationshinweise: IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Reinheit: whole serum

Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Black, Lennon: "Identification and cloning of putative human neuronal voltage-gated calcium channel gamma-2 and gamma-3 subunits: neurologic implications." in: Mayo Clinic proceedings. Mayo Clinic, Vol. 74, Issue 4, pp. 357-61, 1999 (PubMed).

Loftus, Kim, Sneddon et al.: "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q." in: Genomics, Vol. 60, Issue 3, pp. 295-308, 1999 (PubMed).