CACNA1D Antikörper

Produktnummer ABIN350139

Produktdetails anti-CACNA1D Antikörper

Target: CACNA1D (Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CACNA1D Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Spezifität: Specific for Cav1.3

Kreuzreaktivität: Human, Maus, Ratte

Kreuzreaktivität (Details): Other species not yet tested.

Aufreinigung: IgG

Immunogen: A synthetic peptide from human Cav1.3 conjugated to blue carrier protein was used as the antigen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Handhabung: Avoid freeze and thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu CACNA1D

Target: CACNA1D (Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D))

Andere Bezeichnung: CACNA1D (CACNA1D Produkte)

Synonyme: cacna1d antikoerper, cav1.3a antikoerper, isl antikoerper, si:dz136d19.3 antikoerper, si:dz223c6.1 antikoerper, ca(v)1.3 antikoerper, cav1.3 antikoerper, CACH3 antikoerper, CACN4 antikoerper, CACNL1A2 antikoerper, CCHL1A2 antikoerper, Cav1.3 antikoerper, SANDD antikoerper, 8430418G19Rik antikoerper, C79217 antikoerper, Cacnl1a2 antikoerper, Cchl1a antikoerper, Cchl1a2 antikoerper, D-LTCC antikoerper, calcium channel, voltage-dependent, L type, alpha 1D subunit, a antikoerper, calcium voltage-gated channel subunit alpha1 D antikoerper, calcium channel, voltage-dependent, L type, alpha 1D subunit antikoerper, calcium channel, voltage-dependent, L type, alpha 1D subunit L homeolog antikoerper, cacna1da antikoerper, CACNA1D antikoerper, cacna1d antikoerper, cacna1d.L antikoerper, Cacna1d antikoerper

Hintergrund: Function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). Subcellular location: Membrane, Multi-pass membrane protein. Tissue specificity: Expressed in pancreatic islets and in brain, where it has been seen in hippocampus, basal ganglia, habenula and thalamus. No expression in skeletal muscle.,Alpha Subunit,Voltage-dependent L-type calcium channel subunit alpha-1D, Voltage-gated calcium channel subunit alpha Cav1.3, Calcium channel, L type, alpha-1 polypeptide, CACH3, CACN4, CACNL1A2, CCHL1A2, Cav3.1

UniProt: Q01668

Pathways: Sensory Perception of Sound