Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CACNA1C Antikörper (AA 50-100)

CACNA1C Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN350137
  • Target Alle CACNA1C Antikörper anzeigen
    CACNA1C (Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C))
    Bindungsspezifität
    • 12
    • 9
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-100
    Reaktivität
    • 33
    • 21
    • 21
    • 15
    • 1
    • 1
    Human
    Wirt
    • 28
    • 16
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 32
    • 15
    Polyklonal
    Konjugat
    • 25
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CACNA1C Antikörper ist unkonjugiert
    Applikation
    • 30
    • 23
    • 19
    • 17
    • 15
    • 13
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    Specific for CACNA1C.
    Kreuzreaktivität
    Human, Maus, Ratte
    Kreuzreaktivität (Details)
    Other species not yet tested.
    Aufreinigung
    IgG
    Immunogen
    A synthetic peptide from AA 50-100 of human CACNA1C conjugated to blue carrier protein was used as the antigen. The antigen shares 96% identity with mouse, rat and rabbit sequence.
    Isotyp
    IgG
    Top Product
    Discover our top product CACNA1C Primärantikörper
  • Applikationshinweise
    IHC, WB (confirmed by recombinant protein). A dilution of 1 : 1000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
    Handhabung
    Avoid freeze and thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CACNA1C (Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C))
    Andere Bezeichnung
    CACNA1C (CACNA1C Produkte)
    Synonyme
    CACH2 antikoerper, CACN2 antikoerper, CACNL1A1 antikoerper, CCHL1A1 antikoerper, CaV1.2 antikoerper, LQT8 antikoerper, TS antikoerper, Cav1.2 antikoerper, Cchl1a1 antikoerper, MBC antikoerper, MELC-CC antikoerper, RATIVS302 antikoerper, isl antikoerper, C-LTCC antikoerper, CHCACHA1C antikoerper, ICA antikoerper, cav1.2 antikoerper, ca(v)1.2 antikoerper, CAV1.2 antikoerper, BCR antikoerper, rbc antikoerper, calcium voltage-gated channel subunit alpha1 C antikoerper, calcium channel, voltage-dependent, L type, alpha 1C subunit antikoerper, voltage-dependent L-type calcium channel subunit alpha-1C antikoerper, calcium channel, voltage-dependent, L type, alpha 1C subunit S homeolog antikoerper, Red blood cell count antikoerper, RNA, 7SL, cytoplasmic 263, pseudogene antikoerper, CACNA1C antikoerper, Cacna1c antikoerper, cacna1c antikoerper, LOC100442085 antikoerper, cacna1c.S antikoerper, RBC antikoerper, RN7SL263P antikoerper
    Hintergrund
    Function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1C gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing the alpha-1C subunit play an important role in excitation-contraction coupling in the heart. The various isoforms display marked differences in the sensitivity to DHP compounds. Subcellular location: Membrane, Multi-pass membrane protein. Tissue specificity: Expressed in brain, heart, jejunum, ovary, pancreatic beta-cells and vascular smooth muscle. Overall expression is reduced in atherosclerotic vascular smooth muscle.,Alpha Subunit,CACH2, CACN2, CACNL1A1, CCHL1A1, Voltage-gated calcium channel subunit alpha Cav1.2, Calcium channel, L type, alpha-1 polypeptide, cardiac muscle, Voltage dependent L-type calcium channel subunit alpha-1C
    UniProt
    Q13936
    Pathways
    Hormone Transport, Carbohydrate Homeostasis
Sie sind hier:
Kundenservice