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Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (4th cytoplasmic loop) Antikörper

Antigen

Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2)
Epitope
Alternativen

4th cytoplasmic loop
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen
Reaktivität
Applikation
Alternativen Immunhistochemie (IHC), Western Blot (WB)
2 Publikationen vorhanden
Produktnummer ABIN350003
Menge 100 µl  (Varianten)
Preis 317,95 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung
Anwendungen Publikationen Alternativen Sekundärantikörper Varianten zurück nach oben

Weitere Bezeichnung polycystic kidney disease 2 protein homolog (PKD2, Polycystin-2, PC2,TRPP2) (4th cytoplasmic loop)
Swiss-Prot O35245
Immunogen A synthetic peptide from the 4th cytoplasmic loop of mouse, rat Polycystic kidney disease 2 protein homolog (PKD2, Polycystin-2, PC2, TRPP2) conjugated to an immunogenic carrier protein was used as the immunogen.
Format Lyophilized
Beschreibung FUNCTION: Functions as a calcium permeable cation channel. PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. SUBUNIT: Interacts with PKD1. PKD1 requires the presence of PKD2 for stable expression. Interacts with CD2AP. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in mesenchymally derived structures in the developing embryo at day 12.5. In adult, mostly expressed in kidney. Also known as: PKD2, Polycystin-2, PC2, TRPP2.
Spezifität Appears to be specific for PKD2.

Anwendungen
Publikationen Alternativen Sekundärantikörper Varianten zurück nach oben

Applikationshinweise IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Reinheit whole serum
Lagerung Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Beschränkungen Nur für Forschungszwecke einsetzbar

Publikationen
Anwendungen Alternativen Sekundärantikörper Varianten zurück nach oben

Publikationen Wu, Mochizuki, Le et al.: "Molecular cloning, cDNA sequence analysis, and chromosomal localization of mouse Pkd2." in: Genomics, Vol. 45, Issue 1, pp. 220-3, 1997 (PubMed).

Pennekamp, Bogdanova, Wilda et al.: "Characterization of the murine polycystic kidney disease (Pkd2) gene." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 9, Issue 9, pp. 749-52, 1999 (PubMed).

Alternativen
Anwendungen Publikationen Sekundärantikörper Varianten zurück nach oben

Alternativen zu Antigen "Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2)", Typ "Antikörper" finden
Wirte Kaninchen (21), Ziege (1)
Reaktivitäten Human (22), Maus (20), Ratte (Rattus) (19), Huhn (17), Rind (Kuh) (16), Hund (16), Schwein (1), Kaninchen (1)
Applikationen Durchflusszytometrie (FACS) (18), Immunfluoreszenz (IF) (18), Western Blot (WB) (5), ELISA (4), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunhistochemie (Paraffinschnitte) (IHC (p)) (2), Immunpräzipitation (IP) (2), Immunoelectron Microscopy (IEM) (1), Immunhistochemie (IHC) (1)
Konjugate Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitope 4th cytoplasmic loop (1)